3221-14-5

Basic information

• Product Name: Thiirane,2-(phenoxymethyl)-
• Synonyms: Ether,2,3-epithiopropyl phenyl (6CI,7CI,8CI); Thiirane, (phenoxymethyl)- (9CI);2-(Phenoxymethyl)thiirane; 3-Phenoxypropylene sulfide; Phenoxypropylenesulfide; Phenyl thioglycidyl ether; Propane, 1,2-epithio-3-phenoxy-
• CAS NO: 3221-14-5
• Molecular Formula: C9H10 O S
• Molecular Weight: 166.244
• Mol File: 3221-14-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Thiirane,2-(phenoxymethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiirane,2-(phenoxymethyl)-(3221-14-5)
• EPA Substance Registry System: Thiirane,2-(phenoxymethyl)-(3221-14-5)

Safety Data

• Hazardous Substances Data: 3221-14-5(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 122-60-1 Phenyl glycidyl ether 
• 108-95-2 phenol 
• 1147550-11-5 ammonium thiocyanate 
• 333-20-0 potassium thioacyanate 

Downstream Products

• 1746-13-0 allyl phenyl ether 
• 908040-07-3 C₉H₁₃NOS 
• 867018-44-8 1-N,N-dibenzylamino-3-phenoxy-2-propylmercaptan 
• 136197-47-2 2,5-bis(phenoxymethyl)-1,4-dithiane 
• 101414-35-1 6-phenoxy-5-methylphenoxy-4-thia-1-hexene 
• 10414-73-0 4-(phenoxymethyl)-1,3-dithiolane-2-thione 

Relevant articles and documents

An Investigation on the Production of Random Copolymer with Monothiocarbonate and Trithiocarbonate Units over Cyclic Thiocarbonate via Metal-free Catalysis

Synthesis of poly(thiocarbonate)s from the copolymerization of epoxides and carbon disulfide (CS2) remains a tough challenge, due to inevitable oxygen-sulfur atom scrambling process. In this work, we utilized the oxygen-sulfur exchange reaction

Facile synthesis of thietanes via ring expansion of thiiranes

Thietanes are pharmaceutically important cores of some biological compounds and intermediates of organic synthesis. Various thietanes were prepared from thiiranes via ring expansion through a reaction with trimethyloxosulfonium iodide in the presence of sodium hydride. The reaction process is a nucleophilic ring-opening reaction of thiiranes with dimethyloxosulfonium methylide, generated from trimethyloxosulfonium iodide and sodium hydride, and subsequent intramolecular displacement (cyclization) of thiolates to the dimethyloxosulfonium moiety. The current method provides a new strategy for efficient preparation of thietanes from readily available thiiranes.

Conversion of epoxides into 2-hydroxyethyl thiocyanates with NH 4SCN in the presense of 2,6-BIS[2-(O-amino phenoxy)methyl]-4-bromo-1- methoxybenzene (BABMB) as catalyst

A convenient and efficient procedure for the ring-opening of 1,2-epoxyethanes with ammonium thiocyanate in the presence of 2,6-bis[2-(o-aminophenoxy)methyl]-4-bromo-1-methoxybenzene (BABMB) is described. In this study, a reagent and conditions have been discovered with which the individual 2-hydroxyethyl thiocyanates can be synthesized in high yield and with more than 90% regioselectivity. Thus, several 2-hydroxyethyl thiocyanates, useful intermediates toward biological-active molecules, are easily obtained in very good yields.