32212-73-0 Usage
Description
5α,6β-Dibromostigmastan-3β-yl 3-Acetate is a white solid chemical compound derived from the stigmasterol molecule, a plant sterol. It is characterized by the presence of two bromine atoms at the 5α and 6β positions, and an acetate group at the 3β position. This unique structure endows it with specific chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
5α,6β-Dibromostigmastan-3β-yl 3-Acetate is used as a reactant in the preparation of methylenecholestendiol, a synthetic steroidal compound with potential therapeutic applications. It is also used in the synthesis of phytosterols, which are plant-derived compounds that have cholesterol-lowering properties and can be used in the development of drugs for treating hypercholesterolemia and other cardiovascular diseases.
Used in Chemical Research:
As a white solid with distinct chemical properties, 5α,6β-Dibromostigmastan-3β-yl 3-Acetate can be utilized in chemical research for studying the effects of bromination and acetylation on the stigmasterol molecule. This can provide insights into the structure-activity relationships of related compounds and contribute to the development of new pharmaceutical agents or other applications.
Used in Cosmetics Industry:
Due to its chemical stability and potential biological activity, 5α,6β-Dibromostigmastan-3β-yl 3-Acetate may find use in the cosmetics industry as an ingredient in skincare products. It could potentially be incorporated into formulations for its moisturizing, anti-inflammatory, or other beneficial properties, depending on further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 32212-73-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,2,1 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 32212-73:
(7*3)+(6*2)+(5*2)+(4*1)+(3*2)+(2*7)+(1*3)=70
70 % 10 = 0
So 32212-73-0 is a valid CAS Registry Number.
32212-73-0Relevant articles and documents
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Ruzicka,Fischer,Meyer
, p. 1483,1486 (1935)
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NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF
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, (2016/02/16)
Provided are methods of evaluating or treating a patient, e.g., a patient having a disorder described herein, comprising: a) optionally, acquiring a patient sample; b) acquiring an evaluation of and/or evaluating the sample for an alteration in the level S24(S)-hydroxycholesterol compared to a reference standard.
Synthesis of polyhydroxysterols (I): Synthesis of 24-methylenecholest-4-en-3β,6β-diol, a cytotoxic natural hydroxylated sterol
Cui, JianGuo,Zeng, LongMei,Su, JingYu,Lu, WeiGang
, p. 33 - 38 (2007/10/03)
Starting from stigmasterol (2), 24-methylenecholest-4-en-3β,6β-diol (1), a cytotoxic natural dihydroxylated sterol, was synthesized via 10 steps in 20% overall yield. The introduction of a side-chain of sterol was achieved by solid-liquid phase-transfer Wittig reaction using (3-methyl-2-oxo)butyltriphenylarsonium bromide (12) and K2CO3. Construction of the steroidal nucleus was finished by the addition of 3β-acetoxycholest-5,6-en-24-one (7) with NBA in dioxane under ambient temperature and by the elimination of 3β, 6β-diacetoxy-5a-bromocholestane-24-one (9). The spectral data of the synthetic product (1) are completely consistent with those of the natural compound (1). Copyright (C) 2001 Elsevier Science Inc.
