32233-44-6

Basic information

• Product Name: (4S)-2,2-Dimethyl-1,3-Dioxolane-4-Acetaldehyde
• Synonyms: (4S)-2,2-Dimethyl-1,3-Dioxolane-4-Acetaldehyde;1,3-dioxolane-4-acetaldehyde,2,2-dimethyl-(4S);(S)-2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde;2,2-DiMethyl-(4S)-1,3-dioxolane-4-acetaldehyde;2-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acetaldehyde
• CAS NO: 32233-44-6
• Molecular Formula: C₇H₁₂O₃
• Molecular Weight: 144.16838
• Mol File: 32233-44-6.mol
• Article Data: 66

Chemical Properties

• Boiling Point: 73-74 °C(Press: 11 Torr)
• Appearance: /
• Density: 1.000±0.06 g/cm3(Predicted)
• CAS DataBase Reference: (4S)-2,2-Dimethyl-1,3-Dioxolane-4-Acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-2,2-Dimethyl-1,3-Dioxolane-4-Acetaldehyde(32233-44-6)
• EPA Substance Registry System: (4S)-2,2-Dimethyl-1,3-Dioxolane-4-Acetaldehyde(32233-44-6)

Safety Data

• Hazardous Substances Data: 32233-44-6(Hazardous Substances Data)

Usage

General Description

(4S)-2,2-Dimethyl-1,3-Dioxolane-4-Acetaldehyde is a chemical compound with the molecular formula C6H10O2. It is a colorless liquid with a slightly sweet odor and is commonly used as a flavoring agent in the food industry. (4S)-2,2-Dimethyl-1,3-Dioxolane-4-Acetaldehyde is also used in the synthesis of pharmaceuticals and can be found in some fragrances and perfumes. It is important to handle this chemical with care, as it can cause irritation to the skin, eyes, and respiratory system upon exposure. Additionally, it may have harmful effects on aquatic organisms if released into the environment.

Upstream product

• 97-67-6 (S)-Malic acid 
• 103795-10-4 (2R,3R)-1,2-O-Isopropylidene-3-(2-thiazolyl)-1,2,3-propanetriol 
• 85287-65-6 3,5-dinitrobenzoate of (3S)-3,4-(isopropylidenedioxy)butan-1-ol 
• 126946-55-2 ethyl (2rac,3R)-3,4-O-isopropylidene-2-chloro-3,4-dihydroxybutane 
• 126946-54-1 ethyl (2R,3R)-3,4-O-isopropylidene-2-p-toluenesulfonyl-3,4-dihydroxybutanoate 
• 114184-94-0 ethyl (R)-2-[(4'R)-2',2'-dimethyl-1,3-dioxolan-4'-yl]-2-hydroxyacetate 
• 50271-42-6 5,6-O-isopropylidene-D-isoascorbic acid 
• 111205-95-9 2-deoxy-3,4-O-isopropylidene-D-glycero-tetrose diethyldithioacetal 
• 126946-52-9 ethyl (3S)-3,4-dihydroxy-3,4-O-isopropylidene-butanoate 
• 67-64-1 acetone 
• 119991-37-6 (R)-1,2-O-Isopropylidene-3-(2-thiazolyl)-1,2-propanediol 
• 95422-24-5 methyl (3S)-3,4-O-isopropylidene-3,4-dihydroxybutanoate 
• 617-55-0 dimethyl (S)-malate 
• 32233-43-5 2-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]ethanol 

Downstream Products

• 110822-71-4 Benzoic acid (4Z,7Z)-(S)-2-hydroxy-11-methoxycarbonyl-undeca-4,7-dienyl ester 
• 6007-22-3 2,2-dimethyl-1,3-dithiane 
• 120409-53-2 2-((2S)-2,3-O-isopropylidene-2,3-dihydroxypropyl)-1,3-dithiane 
• 141206-91-9 (S)-2-(2',3'-dihydroxypropyl)-1,3-dithiane 
• 637363-42-9 (4R)-4-benzyl-3-[(2R,3S)-4-((4S)-2,2-dimethyl-1,3-dioxolan-4-yl)-3-hydroxy-2-methylsulfanylbutanoyl]-1,3-oxazolan-2-one 
• 809276-03-7 N-[(S)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-hydroxy-butyryl]-benzamide 
• 809276-04-8 N-[(R)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-hydroxy-butyryl]-benzamide 
• 809276-28-6 N-{(S)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-[1-(2-hydroxy-phenyl)-meth-(E)-ylideneaminooxy]-butyryl}-benzamide 
• 809276-29-7 N-{(R)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-[1-(2-hydroxy-phenyl)-meth-(E)-ylideneaminooxy]-butyryl}-benzamide 
• 81662-58-0 4-Nitro-benzoic acid (S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-tetradec-13-enyl ester 
• 81662-59-1 4-Nitro-benzoic acid (R)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-tetradec-13-enyl ester 
• 101977-99-5 (4S)-4-<(2S,7R)-(4E)-8-benzyloxy-2-hydroxy-5,7-dimethyloct-4-en-1-yl>-2,2-dimethyl-1,3-dioxolane 
• 1496558-46-3 (S,E)-4-(2,2-dimethyl-1,3-dioxolan-4-yl)-1-phenylbut-2-en-1-one 
• 1496558-67-8 (2S,4S,6R)-(6-methyl-4-((E)-styryl)tetrahydro-2H-pyran-2-yl)-methanol 

Relevant articles and documents

Modular strategies for structure and function employed by marine cyanobacteria: Characterization and synthesis of pitinoic acids

Novel bioactive lipids were identified from a Guamanian cyanobacterium, the Pseudomonas aeruginosa quorum sensing inhibitor pitinoic acid A (1) and the anti-inflammatory pitinoic acids B (2) and C. The structure of 2 was confirmed by synthesis, which also allowed for biological evaluation. Since 2 is an ester of pitinoic acids A and C, it represents a prodrug strategy to liberate dual biological activity for the management of P. aeruginosa infections and their associated inflammation.

Nickel-Catalyzed Cross-Electrophile Coupling of Alkyl Fluorides: Stereospecific Synthesis of Vinylcyclopropanes

The stereospecific reductive cross-electrophile coupling reaction of 2-vinyl-4-halotetrahydropyrans for vinylcyclopropane synthesis is reported. The nickel-catalyzed reaction occurs with both alkyl fluorides and alkyl chlorides. To the best of our knowledge, this is the first reported cross-electrophile coupling reaction of an alkyl fluoride. Ring contraction proceeds with high stereospecificity, providing selective synthesis of either diastereomer of di- and trisubstituted cyclopropanes. The utility of this methodology is demonstrated by several synthetic applications including the synthesis of the natural product dictyopterene A. 2-Vinyl-4-fluorotetrahydrofurans also undergo stereospecific ring contractions, providing access to synthetically useful hydroxymethyl cyclopropanes.

E-Selectin Antagonists Modified By Macrocycle Formation to the Galactose

Provided herein are glycomimetic E-selectin antagonist compounds of formula (I)) and pharmaceutical compositions comprising at least one of the same. The compounds of the present disclosure include trisaccharide domain mimics comprising at least one macro

E-SELECTIN ANTAGONISTS MODIFIED BY MACROCYCLE FORMATION TO THE GALACTOSE

Provided herein are glycomimetic E-selectin antagonist compounds of formula (I)) and pharmaceutical compositions comprising at least one of the same. The compounds of the present disclosure include trisaccharide domain mimics comprising at least one macro