322473-89-2 Usage
Description
3-Endo-8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol, also known as SCH 221510, is a complex organic compound with a unique bicyclic structure. It features a phenyl group attached to the 3-position and a bis(2-methylphenyl)methyl group at the 8-position, with an alcohol group at the 3-position as well. 3-Endo-8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol has potential applications in the pharmaceutical industry due to its specific molecular structure and properties.
Uses
Used in Pharmaceutical Industry:
3-Endo-8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol is used as a nociceptin/orphanin FQ peptide (μ-opioid) receptor agonist for the treatment of neuropathic and inflammatory pain. Its agonistic activity on the μ-opioid receptors can help alleviate pain by modulating the pain signaling pathways in the central nervous system.
Additionally, 3-Endo-8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol has potential as an anti-inflammatory agent. Its anti-inflammatory properties may be beneficial in reducing inflammation associated with various conditions, such as arthritis or other inflammatory disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 322473-89-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,2,4,7 and 3 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 322473-89:
(8*3)+(7*2)+(6*2)+(5*4)+(4*7)+(3*3)+(2*8)+(1*9)=132
132 % 10 = 2
So 322473-89-2 is a valid CAS Registry Number.
322473-89-2Relevant articles and documents
The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety
Ho, Ginny D.,Anthes, John,Bercovici, Ana,Caldwell, John P.,Cheng, Kuo-Chi,Cui, Xiaoming,Fawzi, Ahmad,Fernandez, Xiomara,Greenlee, William J.,Hey, John,Korfmacher, Walter,Lu, Sherry X.,McLeod, Robbie L.,Ng, Fay,Torhan, April Smith,Tan, Zheng,Tulshian, Deen,Varty, Geoffrey B.,Xu, Xiaoying,Zhang, Hongtao
scheme or table, p. 2519 - 2523 (2009/12/25)
The discovery of 1 as a high-affinity ligand for the nociceptin receptor has led to the synthesis of a series of tropane (8-methyl-8-azabicyclo[3.2.1]octane) derivatives as optimized ligands. These compounds exhibit high affinity for the nociceptin recept
