3232-12-0Relevant articles and documents
Tributylphosphine, excellent organocatalyst for conjugate additions of non-nucleophilic N-containing compounds
Gimbert, Carolina,Moreno-Ma?as, Marcial,Pérez, Elisabet,Vallribera, Adelina
, p. 8305 - 8310 (2008/02/05)
Conjugate additions of non-nucleophilic N-containing compounds such as amides, thioamides, sulfonamides, and electron-poor anilines with different Michael acceptors can be promoted through the use of tributylphosphine. The range of useful pKa's of nucleophiles has been established (pKa25) and new insights into the mechanism proposed.