32386-95-1

Basic information

• Product Name: 2-(benzylideneamino)-1H-isoindole-1,3(2H)-dione
• Synonyms: 2-(benzylideneamino)-1H-isoindole-1,3(2H)-dione
• CAS NO: 32386-95-1
• Molecular Weight: 250.257
• Mol File: 32386-95-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(benzylideneamino)-1H-isoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzylideneamino)-1H-isoindole-1,3(2H)-dione(32386-95-1)
• EPA Substance Registry System: 2-(benzylideneamino)-1H-isoindole-1,3(2H)-dione(32386-95-1)

Safety Data

• Hazardous Substances Data: 32386-95-1(Hazardous Substances Data)

Upstream product

• 1875-48-5 N-aminophthalamide 
• 100-52-7 benzaldehyde 

Downstream Products

• 5004-45-5 4-phenyl-2H-phthalazin-1-one 
• 1390649-45-2 2-((benzylidenehydrazono)(phenyl)methyl)benzophenone 
• 1390649-47-4 2-((benzylidenehydrazono)(2,4-dimethylphenyl)methyl)-4',6'-dimethylbenzophenone 
• 1390649-48-5 2-((benzylidenehydrazono)(p-methoxyphenyl)methyl)-4'-methoxybenzophenone 
• 1390649-49-6 2-((benzylidenehydrazono)(p-bromophenyl)methyl)-4'-bromobenzophenone 
• 614-31-3 N-benzyl-N-phenylhydrazine 
• 530740-37-5 2-(N-benzyl-anilino)-isoindoline-1,3-dione 
• 643752-17-4 acetic acid 2-(benzyl-methyl-amino)-3-oxo-2,3-dihydro-1H-isoindol-1-yl ester 
• 643752-18-5 acetic acid 2-benzylamino-3-oxo-2,3-dihydro-1H-isoindol-1-yl ester 
• 643752-10-7 2-[benzyl(methyl)amino]-3-hydroxy-2,3-dihydro-1H-isoindol-1-one 
• 643752-13-0 2-(benzylamino)-3-hydroxy-2,3-dihydro-1H-isoindol-1-one 
• 643752-05-0 2-(benzyl-methyl-amino)-isoindole-1,3-dione 

Relevant articles and documents

Extending the Scope of the B(C6F5)3-Catalyzed C=N Bond Reduction: Hydrogenation of Oxime Ethers and Hydrazones

The B(C6F5)3-catalyzed hydrogenation is applied to aldoxime triisopropylsilyl ethers and hydrazones bearing an easily removable phthaloyl protective group. The C=N reduction of aldehyde-derived substrates (oxime ethers and hydrazones) is enabled by using 1,4-dioxane as the solvent known to participate as the Lewis-basic component in FLP-type heterolytic dihydrogen splitting. More basic ketone-derived hydrazones act as Lewis bases themselves in the FLP-type dihydrogen activation and are therefore successfully hydrogenated in nondonating toluene. The difference in reactivity between aldehyde- and ketone-derived substrates is also reflected in the required catalyst loading and dihydrogen pressure.

A convenient synthesis of 1-alkyl-1-phenylhydrazines from N-aminophthalimide

N-Alkylaminophthalimides were synthesized by condensation of N-aminophthalimide with aldehydes, and subsequent reduction of the intermediate with pyridine-borane in acetic acid. N-Phenylation and removal of the phthalimide group gave 1-alkyl-1-phenylhydrazines in high yield.