32431-36-0

Basic information

• Product Name: 2,3-dimethyl-2,3-dihydroisoquinoline
• CAS NO: 32431-36-0
• Molecular Formula: C₁₁H₁₂N*I
• Molecular Weight: 159.2276
• Mol File: 32431-36-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 352°C at 760 mmHg
• Flash Point: 150.7°C
• Density: 1.04g/cm³
• Vapor Pressure: 3.94E-05mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: 2,3-dimethyl-2,3-dihydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dimethyl-2,3-dihydroisoquinoline(32431-36-0)
• EPA Substance Registry System: 2,3-dimethyl-2,3-dihydroisoquinoline(32431-36-0)

Safety Data

• Hazardous Substances Data: 32431-36-0(Hazardous Substances Data)

Usage

General Description

2,3-dimethyl-2,3-dihydroisoquinoline is a chemical compound that belongs to the isoquinoline class. It is a bicyclic organic molecule containing a isoquinoline core with two methyl groups attached to the second and third positions. 2,3-dimethyl-2,3-dihydroisoquinoline is used in the research and pharmaceutical industry for its potential biological activities, including antiviral and antitumor properties. It has also been studied for its potential in the treatment of neurodegenerative diseases such as Parkinson's and Alzheimer's. Additionally, it is used as a building block in the synthesis of various organic compounds and can be produced through chemical reactions such as Friedel-Crafts alkylation. Overall, 2,3-dimethyl-2,3-dihydroisoquinoline is a versatile and important chemical with potential applications in various fields.

Upstream product

• 1125-80-0 3-methylisoquinoline 
• 74-88-4 methyl iodide 

Downstream Products

• 51650-27-2 1-benzyl-3-methylisoquinoline 
• 1125-80-0 3-methylisoquinoline 
• 2216-67-3 2-N-methylaminonaphthalene 
• 7114-78-5 2,3-Dimethyl-1-oxo-1,2-dihydroisoquinoline 
• 2437-03-8 2-ethylaminonaphthalene 
• 135-19-3 β-naphthol 
• 113164-18-4 3-(4-dimethylamino-trans-styryl)-2-methyl-isoquinolinium; iodide 
• 109726-75-2 2-methyl-3-trans-styryl-isoquinolinium; iodide 
• 54365-72-9 2,3-Dimethyl-1,2,3,4-tetrahydroisoquinoline 
• 34140-16-4 2-methyl-3-(3-nitro-trans-styryl)-isoquinolinium; iodide 

Relevant articles and documents

Electrochemical regioselective selenylation/oxidation of: N-alkylisoquinolinium salts via double C(sp2)-H bond functionalization

An efficient, novel, and environmentally friendly electrochemical regioselective selenylation/oxidation of N-alkylisoquinolinium salts via double C(sp2)-H bond functionalization under undivided electrolytic conditions has been developed. A series of selenide isoquinolones were easily accessed through this sustainable and clean electrochemical system. The present protocol was further extended to afford selenide quinolones and 1,3-dimethyl-1H-benzo[d]imidazol-2(3H)-ones. Furthermore, antiviral bioassays demonstrated that compound 3j exhibited excellent antiviral activity against tobacco mosaic virus (TMV), and its inhibition rate was up to 90%. This journal is

Transfer hydrogenation of isoquinolinium salts catalyzed by a rhodium complex

Regio- and chemoselective transfer hydrogenation of isoquinolinium salts catalyzed by [Cp*RhCl2]2 using HCOOH-Et3N (5:2) as a hydrogen source was realized. A variety of N-methyl- and N-benzyl-1,2,3,4-tetrahydroisoquinoline

Indium metal as a reducing agent in organic synthesis

The low first ionisation potential (5.8 eV) of indium coupled with its stability towards air and water, suggest that this metallic element should be a useful reducing agent for organic substrates. The use of indium metal for the reduction of C=N bonds in imines, the heterocyclic ring in benzo-fused nitrogen heterocycles, of oximes, nitro compounds and conjugated alkenes and the removal of 4-nitrobenzyl protecting groups is described. Thus the heterocyclic ring in quinolines, isoquinolines and quinoxalines is selectively reduced using indium metal in aqueous ethanolic ammonium chloride. Treatment of a range of aromatic nitro compounds under similar conditions results in selective reduction of the nitro groups; ester, nitrile, amide and halide substituents are unaffected. Likewise indium in aqueous ethanolic ammonium chloride is an effective method for the deprotection of 4-nitrobenzyl ethers and esters. Indium is also an effective reducing agent under non-aqueous conditions and α-oximino carbonyl compounds can be selectively reduced to the corresponding N-protected amine with indium powder, acetic acid in THF in the presence of acetic anhydride or di-tert-butyl dicarbonate. Conjugated alkenes are also reduced by indium in THF-acetic acid.