324519-77-9Relevant articles and documents
Tricyclic compounds having sPLA2-inhibitory activities
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Page column 25, (2010/02/05)
The present invention provides a compound having sPLA2inhibiting activity. The compound represented by the formula (I): wherein R1is (a) C1 to C20 alkyl, C2 to C20 alkenyl, C2 to C20 alkynyl, carbocyclic groups, heterocyclic groups or the like; R2is CONH2or CONHNH2; one of R3and R4is —(L2)-(acidic group) wherein L2is a group connecting with an acid group and the length of the connecting groups 1 to 5 atoms, and the other is a hydrogen atom; its prodrug, their pharmaceutically acceptable salt, or solvate thereof.