32477-35-3 Usage
Description
N-Heptafluorobutyrylimidazole is a colorless liquid that may form a precipitate and darken on storage, but this does not affect its performance. It is a derivatization agent used in gas chromatography for the determination of various pharmaceutical compounds.
Uses
Used in Pharmaceutical Analysis:
N-Heptafluorobutyrylimidazole is used as a reagent for derivatizing amine groups in gas chromatography. It plays an essential role in reducing GC column degradation due to its non-acidic property. As an acylating agent, it converts thermally unstable compounds to their more volatile derivatives, making them suitable for GC analysis.
Used in Gas Chromatography:
N-Heptafluorobutyrylimidazole is used as a derivatization agent in gas chromatography for the determination of various pharmaceutical compounds, such as retronecine, in biological matrixes. This allows for the accurate identification and quantification of these compounds in complex biological samples.
Biochem/physiol Actions
Mild amine-group derivatizing reagent; non-acidic by-product prevents decomposition and reduces GC column degradation.
Check Digit Verification of cas no
The CAS Registry Mumber 32477-35-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,4,7 and 7 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 32477-35:
(7*3)+(6*2)+(5*4)+(4*7)+(3*7)+(2*3)+(1*5)=113
113 % 10 = 3
So 32477-35-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H10FN.ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;/h1-8H,14H2;1H
32477-35-3Relevant articles and documents
Synthesis of novel 2-perfluoroacylcyclohexane-1,3-diones
Khlebnicova,Isakova,Baranovsky,Borisov,Lakhvich
, p. 1564 - 1569 (2008/09/18)
A one-pot synthesis of 2-perfluoroalkanoylcyclohexane-1,3-diones via C-acylation of cyclohexane-1,3-diones with N-perfluoroacylimidazole as an acylating agent is reported. A reaction was examined with isolated N-trifluoroacetylimidazole and with N-perfluoroacylimidazoles generated in situ from perfluorocarboxylic acid anhydrides or perfluorocarboxylic acids.
