32483-51-5 Usage
Description
Ethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methylhex-4-enoate is a complex organic compound that is a derivative of mycophenolic acid. It is characterized by its unique molecular structure, which includes a hydroxy, methoxy, and methyl groups attached to an isobenzofuran core. ethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methylhex-4-enoate is known for its potential biological activities and applications in various fields.
Uses
Used in Cancer Research:
Ethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methylhex-4-enoate is used as a research compound in cancer studies. It is employed to investigate the antitumor activity of mycophenolate derivatives as neoplasm inhibitors. ethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methylhex-4-enoate's unique structure and functional groups may contribute to its potential as a therapeutic agent against cancer.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, ethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methylhex-4-enoate is used as an impurity of mycophenolic acid (M831500), with the CAS number 24280-93-1. Its presence in mycophenolic acid may have implications for the drug's efficacy and safety, making it important to study and control its levels in pharmaceutical formulations.
Used in Drug Development:
Ethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methylhex-4-enoate may also be used in drug development as a potential lead compound for the design of new therapeutic agents. Its unique chemical structure and biological activities could inspire the development of novel drugs with improved efficacy and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 32483-51-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,4,8 and 3 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 32483-51:
(7*3)+(6*2)+(5*4)+(4*8)+(3*3)+(2*5)+(1*1)=105
105 % 10 = 5
So 32483-51-5 is a valid CAS Registry Number.
32483-51-5Relevant articles and documents
Phosphamide derivative as well as preparation method and application thereof
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Paragraph 0692; 0695-0701, (2019/02/19)
The invention relates to a compound of a general formula (I), a stereoisomer or pharmaceutically acceptable salt of the compound and application of the compound in preparation of medicines for preventing or treating diabetes, resisting tumors, preventing or treating attention deficit hyperactivity disorder and motor neuron diseases, protecting brain and preventing or treating central nervous system related diseases, immunosuppression, organ tissue or cell allogeneic suppression rejection reaction, immune regulation and/or inflammatory diseases, convulsions, epilepsy or cerebral apoplexy. The structure of the compound of the general formula (I) is Q-L-R, and the groups of the compound are defined in the specification.
The synthesis of mycophenolic acid
Patterson, John W.
, p. 4789 - 4798 (2007/10/02)
A new synthesis of mycophenolic acid 1, has been accomplished using silyloxy-1,3-cyclohexadiene 9 which undergoes cycloaddition to dimethyl acetylenedicarboxylate and subsequent elimination of ethylene (Alder-Rickert reaction) to give the trisubstituted dimethyl phthalate 11. After conversion of 11 to phthalide 16, the (E)-4-methyl-4-hexenoic acid side-chain was constructed via an orthoester Claisen rearrangement using allylic alcohol 19 and triethyl orthoacetate.
