32687-77-7Relevant articles and documents
Synthetic process for antioxidant 1024
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Paragraph 0038; 0039; 0047; 0048; 0056; 0057; 0063; 0064, (2018/09/21)
The invention provides a synthetic method for an organic synthesis antioxidant 1024, that is, a synthetic method for N,N'-bis[beta(3,5-di-tert-butyl-4-hydroxyphenyl)propionyl]hydrazine. The preparation method comprises the following steps: firstly synthesizing beta-(3,5-di-tert-butyl-4-hydroxyphenyl)propanohydrazide by using hydrazine hydrate and beta-(3,5-di-tert-butyl-4-hydroxyphenyl)methyl propionate as raw materials, and synthesizing the N,N'-bis[beta(3,5-di-tert-butyl-4-hydroxyphenyl)propionyl]hydrazine by using the beta-(3,5-di-tert-butyl-4-hydroxyphenyl)propanohydrazide and ethyl acetoacetate as raw materials. According to the method provided by the invention, a solvent type, a mass ratio of one reactant to another reactant and a mass volume ratio of reactants to solvents in a reaction system are adjusted, so that the reaction is performed more thoroughly, a product yield is greatly improved, and the product yield in a pilot plant test can still be guaranteed to be higher than acurrent level.
A method for preparing an antioxidant
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Paragraph 0064; 0067-0068, (2018/02/04)
The invention provides a preparation method for an antioxidant. The method includes: subjecting a compound shown as formula (III) and a compound shown s formula (IV) to dehydration reaction in the presence of an organic solvent. The method is characterized in that in the dehydration reaction process, the reaction generated water and part of the organic solvent are separated from the reaction system, and water division treatment is carried out, then the water-containing organic solvent subjected to water division treatment contacts a first dehydrating agent, and the organic solvent obtained after contact is returned to the reaction system. Specifically, n is 1 or 2, x is 1 or 2, y is an integer of 0-6, R1 and R2 are not a straight chain or branched chain alkyl group with a hydrogen atom or carbon atom number of 1-6 at the same time, and R3 and R4 are not a straight chain or branched chain alkyl group with a hydrogen atom or carbon atom number of 1-6 at the same time. By adopting the method provided by the invention to prepare the antioxidant, the dehydration effect of the reaction system can be enhanced, and accordingly the reaction efficiency and product yield can be enhanced. (formula III and formula IV).
Synthesis and chemical transformations of β-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic hydrazide
Ismagilov,Moskva,Lebedev,Mosunova
, p. 931 - 933 (2007/10/03)
A method for synthesis of β-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic hydrazide. Certain chemical properties of the product were studied. It was found that β-(3,5-di-ter-butyl-4-hydroxyphenyl)-propionic β-(3,5-di-tert-butl-4-hydroxyphenyl)hydrazide is highly susceptible to oxidation.