3271-79-2

Basic information

• Product Name: Salutaridinol
• Synonyms: (7S)-5,6,8,14-Tetradehydro-4-hydroxy-3,6-dimethoxy-17-methylmorphinan-7-ol;5,6,8,14-Tetradehydro-3,6-dimethoxy-17-methylmorphinan-4,7α-diol;Salutaridinol II
• CAS NO: 3271-79-2
• Molecular Formula: C₁₉H₂₃NO₄
• Molecular Weight: 329.39022
• Mol File: 3271-79-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 132-140 °C
• Boiling Point: 535.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.33±0.1 g/cm3(Predicted)
• PKA: 9.79±0.60(Predicted)
• CAS DataBase Reference: Salutaridinol(CAS DataBase Reference)
• NIST Chemistry Reference: Salutaridinol(3271-79-2)
• EPA Substance Registry System: Salutaridinol(3271-79-2)

Safety Data

• Hazardous Substances Data: 3271-79-2(Hazardous Substances Data)

Usage

Description

Salutaridinol, also known as M652290, is a metabolic intermediate in the biosynthesis of morphine, which is the principal alkaloid found in opium. It plays a crucial role in the production process of morphine, a widely used analgesic and narcotic drug.

Uses

Used in Pharmaceutical Industry:
Salutaridinol is used as a metabolic intermediate for the production of morphine, an essential alkaloid in the pharmaceutical industry. It is crucial in the biosynthesis process of morphine, which is a widely used analgesic and narcotic drug for pain management and various medical applications.

Downstream Products

• 73378-05-9 (R)-2,10-dimethoxy-11-hydroxyaporphine 
• 478-53-5 Morphothebaine 
• 115-37-7 thebaine 

Relevant articles and documents

A Regio- and Diastereoselective Anodic Aryl–Aryl Coupling in the Biomimetic Total Synthesis of (?)-Thebaine

The biosynthesis of thebaine is based on the regioselective, intramolecular, oxidative coupling of (R)-reticuline. For decades, chemists have sought to mimic this coupling by using stoichiometric oxidants. However, all approaches to date have suffered from low yields or the formation of undesired regioisomers. Electrochemistry would represent a sustainable alternative in this respect but all attempts to accomplish an electrochemical synthesis of thebaine have failed so far. Herein, a regio- and diastereoselective anodic coupling of 3′,4′,5′-trioxygenated laudanosine derivatives is presented, which finally enables electrochemical access to (?)-thebaine.

INVESTIGATIONS ON THE BIOSYNTHESIS OF MORPHINE ALKALOIDS.

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