327175-05-3 Usage
Description
2H-Pyran-2-one, 4-hydroxy-6-(2-oxoheptyl)is a complex organic compound derived from the metabolic processes of Mycobacterium tuberculosis, specifically as a product of Type III Polyketide Synthases. This molecule is characterized by its unique chemical structure, which includes a pyranone ring with a hydroxyl group at the 4-position and a 2-oxoheptyl side chain. 2H-Pyran-2-one, 4-hydroxy-6-(2-oxoheptyl)-'s properties and structure make it a potential candidate for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
2H-Pyran-2-one, 4-hydroxy-6-(2-oxoheptyl)is used as a pharmaceutical compound for its potential therapeutic applications. 2H-Pyran-2-one, 4-hydroxy-6-(2-oxoheptyl)-'s unique structure and properties may allow it to interact with specific biological targets, making it a promising candidate for the development of new drugs. Its production through Mycobacterium tuberculosis, a well-studied bacterium, may also provide insights into its potential uses in treating tuberculosis or other related diseases.
Used in Chemical Research:
In the field of chemical research, 2H-Pyran-2-one, 4-hydroxy-6-(2-oxoheptyl)can be used as a starting material or intermediate for the synthesis of more complex molecules. Its unique structure may enable the development of novel chemical reactions or the creation of new compounds with specific properties and applications.
Used in Material Science:
2H-Pyran-2-one, 4-hydroxy-6-(2-oxoheptyl)-'s structural characteristics may also make it a candidate for use in material science, where it could be employed in the development of new materials with specific properties. For example, its potential to form stable complexes with other molecules could be utilized in the creation of advanced materials with applications in various industries, such as electronics, energy, or environmental protection.
Used in Drug Delivery Systems:
Similar to gallotannin, 2H-Pyran-2-one, 4-hydroxy-6-(2-oxoheptyl)could be used in drug delivery systems to improve the bioavailability and therapeutic outcomes of various drugs. Its unique structure may allow for the development of novel drug carriers or the enhancement of existing drug delivery methods, leading to more effective treatments for a range of diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 327175-05-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,7,1,7 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 327175-05:
(8*3)+(7*2)+(6*7)+(5*1)+(4*7)+(3*5)+(2*0)+(1*5)=133
133 % 10 = 3
So 327175-05-3 is a valid CAS Registry Number.
327175-05-3Relevant articles and documents
Cloning and structure-function analyses of quinolone- and acridone-producing novel type III polyketide synthases from citrus microcarpa
Mori, Takahiro,Shimokawa, Yoshihiko,Matsui, Takashi,Kinjo, Keishi,Kato, Ryohei,Noguchi, Hiroshi,Sugio, Shigetoshi,Morita, Hiroyuki,Abe, Ikuro
, p. 28845 - 28858 (2013/10/22)
Background:Type III polyketide synthases (PKSs) synthesize various polyketide and alkaloid scaffolds. Results:QNS synthesizes quinolone as the single product, whereas ACS produces acridone as the major product. Conclusion:QNS and ACS are novel quinolone- and acridone-producing type III PKSs, respectively. Significance:Structure-function analyses of QNS and ACS provide insights into molecular bases for alkaloid biosyntheses.
In vitro precursor-directed synthesis of polyketide analogues with coenzyme a regeneration for the development of antiangiogenic agents
Kim, Moon I.I.,Kwon, Seok Joon,Dordick, Jonathan S.
supporting information; experimental part, p. 3806 - 3809 (2009/12/09)
Polyketide analogues are produced via in vitro reconstruction of a precursor-directed polyketide biosynthetic pathway. Malonyl-CoA synthetase (MCS) was used in conjunction with chalcone synthase (CHS), thereby allowing efficient use of synthetic starter molecules and malonate as extender. Coenzyme-A was recycled up to 50 times. The use of a simple immobilization procedure resulted in up to a 30-fold higher yield of pyrone CHS products than that obtained with the free enzyme solutions.
Exploiting the reaction flexibility of a type III polyketide synthase through in vitro pathway manipulation
Jeong, Jae-Cheol,Srinivasan, Aravind,Grueschow, Sabine,Bach, Horacio,Sherman, David H.,Dordick, Jonathan S.
, p. 64 - 65 (2007/10/03)
A synthetic metabolic pathway has been constructed in vitro consisting of the type III polyketide synthase from Streptomyces coelicolor and peroxidases from soybean and Caldariomyces fumago (chloroperoxidase). This has resulted in the synthesis of the pentaketide flaviolin and its dimeric derivative, and a wide range of pyrones and their coupled derivatives with flaviolin, as well as their halogenated derivatives. The addition of acyl-CoA oxidase to the pathway prior to the polyketide synthase resulted in unsaturated pyrone side chains, further broadening the product spectrum that can be achieved. The approach developed in this work, therefore, provides a new model to exploit biocatalysis in the synthesis of complex natural product derivatives. Copyright
