3274-63-3

Basic information

• Product Name: ethyl 2-methyl-4-phenyl-1H-pyrrole-3-carboxylate
• Synonyms: 1H-pyrrole-3-carboxylic acid, 2-methyl-4-phenyl-, ethyl ester; Ethyl 2-methyl-4-phenyl-1H-pyrrole-3-carboxylate
• CAS NO: 3274-63-3
• Molecular Formula: C₁₄H₁₅NO₂
• Molecular Weight: 229.2744
• Mol File: 3274-63-3.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 423.7°C at 760 mmHg
• Flash Point: 210°C
• Density: 1.125g/cm³
• Vapor Pressure: 2.2E-07mmHg at 25°C
• Refractive Index: 1.566
• CAS DataBase Reference: ethyl 2-methyl-4-phenyl-1H-pyrrole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-methyl-4-phenyl-1H-pyrrole-3-carboxylate(3274-63-3)
• EPA Substance Registry System: ethyl 2-methyl-4-phenyl-1H-pyrrole-3-carboxylate(3274-63-3)

Safety Data

• Hazardous Substances Data: 3274-63-3(Hazardous Substances Data)

Usage

General Description

Ethyl 2-methyl-4-phenyl-1H-pyrrole-3-carboxylate, also known as Ethyl 2-methyl-4-phenylpyrrole-3-carboxylate, is a synthetic organic compound with the molecular formula C14H15NO2. It is a pyrrole derivative, characterized by a pyrrole ring structure with a phenyl group and an ethyl ester substituent. This chemical compound is commonly used in the pharmaceutical industry as a building block for the synthesis of various biologically active compounds and pharmaceutical drugs. It exhibits potential pharmacological activities, such as antifungal, antimicrobial, and anti-inflammatory properties, making it a valuable intermediate in the development of pharmaceutical products. Additionally, it is also used in scientific research and academic studies as a reference compound for the investigation of pyrrole-based molecules and their potential applications in medicine.

Upstream product

• 626-34-6 ethyl aminocrotonate 
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• 100-52-7 benzaldehyde 
• 201230-82-2 carbon monoxide 
• 3651-13-6 5-methyl-3-phenyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester 
• 60317-41-1 ethyl 2-(hydroxyimino)-3-oxo-3-phenylpropanoate 
• 72709-62-7 ethyl 2-acetyl-4-nitro-3-phenylbutyrate 
• 5153-67-3 nitrostyrene 
• 7568-93-6 2-Amino-1-phenylethanol 
• 591-51-5 phenyllithium 
• 231609-63-5 ethyl 3-((N-methoxy-N-methylcarbamoyl)methylamino)crotonate 

Downstream Products

• 342642-53-9 5-formyl-2-methyl-4-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester 
• 897009-30-2 2-methyl-4-phenyl-pyrrole-3-carboxylic acid 
• 3274-54-2 2-methyl-4-phenyl-1H-pyrrole 

Relevant articles and documents

Pyrrole derivative as well as preparation method and application thereof

The invention belongs to the field of medical chemistry, and relates to a pyrrole derivativex as well as a preparation method and application thereof. A compound with a structure shown as a general formula (I), or one or a mixture of more of a tautomer, a

Synthesis of multisubstituted 1H-pyrrole: Selenium-catalyzed reaction of γ-nitro substituted carbonyl compounds and carbon monoxide

The novel and efficient selenium-catalyzed reductive N-heterocyclization of γ-nitro substituted carbonyl compounds with carbon monoxide has been developed. Various multisubstituted 1H-pyrroles can be easily prepared by this protocol. The one-pot synthesis

Efficient synthesis of pyrroles and 4,5,6,7-tetrahydroindoles via palladium-catalyzed oxidation of hydroxy-enamines

Facile and one-pot synthetic route of poly-substituted pyrroles and 4-oxo-4,5,6,7-tetrahydroindoles is established, which consists of three steps: (1) palladium-catalyzed oxidation of hydroxy-enamines by using tetrakis(triphenylphosphine)palladium and mesityl bromide oxidation system, (2) intramolecular cyclization, and (3) dehydration.