32747-08-3 Usage
Description
Glycohyocholic acid (GHCA) is a glycine-conjugated form of the primary bile acid hyocholic acid. It plays a significant role in various physiological processes and has been found to be upregulated in certain health conditions.
Uses
Used in Medical Applications:
Glycohyocholic acid is used as a biomarker for [application reason] in patients with cirrhosis induced by hepatitis C virus (HCV). The upregulation of GHCA in the serum of these patients compared to healthy controls makes it a valuable indicator for monitoring the condition and its progression.
Used in Post-surgical Recovery Monitoring:
Glycohyocholic acid is used as an indicator of improved health status in patients who are no longer diabetic following gastric bypass surgery. The increase in plasma levels of GHCA in these patients suggests a positive response to the surgical intervention and can be used to assess the effectiveness of the procedure.
Used in Pharmaceutical Industry:
Glycohyocholic acid is used as a bile salt for [application reason] in the development of medications targeting various health conditions. Its role in the body's digestive process and its presence in patients with specific health conditions make it a potential target for therapeutic intervention.
Used in Research and Diagnostics:
Glycohyocholic acid is used as a research tool for [application reason] in understanding the underlying mechanisms of various diseases and conditions. Its upregulation in specific health scenarios provides valuable insights into the pathophysiology of these conditions and can aid in the development of targeted treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 32747-08-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,7,4 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 32747-08:
(7*3)+(6*2)+(5*7)+(4*4)+(3*7)+(2*0)+(1*8)=113
113 % 10 = 3
So 32747-08-3 is a valid CAS Registry Number.
32747-08-3Relevant articles and documents
INHIBITORS OF THE FARNESOID X RECEPTOR AND USES IN MEDICINE
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, (2015/02/25)
Disclosed are inhibitors of the farnesoid X receptor, for example of formula (I), wherein R1, R2, R4, X, Y, Z, m, and n are as defined herein, which are useful in treating or preventing obesity, type 2 diabetes/insulin resistance and non alcoholic fatty liver disease in a mammal in need thereof. Also disclosed is a composition comprising a pharmaceutically suitable carrier and at least one compound of the invention, a method of method of inhibiting a farnesoid X receptor in a mammal, and a method of treating or preventing obesity in a mammal.
