327596-87-2

Basic information

• Product Name: N,N,N',N'-tetraisopropyl-O-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethyl] phosphordiamidite
• Synonyms: N,N,N',N'-tetraisopropyl-O-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethyl] phosphordiamidite
• CAS NO: 327596-87-2
• Molecular Weight: 467.632
• Mol File: 327596-87-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N,N,N',N'-tetraisopropyl-O-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethyl] phosphordiamidite(CAS DataBase Reference)
• NIST Chemistry Reference: N,N,N',N'-tetraisopropyl-O-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethyl] phosphordiamidite(327596-87-2)
• EPA Substance Registry System: N,N,N',N'-tetraisopropyl-O-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethyl] phosphordiamidite(327596-87-2)

Safety Data

• Hazardous Substances Data: 327596-87-2(Hazardous Substances Data)

Upstream product

• 56183-63-2 bis(diisopropylamino)chlorophosphine 
• 291299-78-0 N-(2-hydroxyethyl)-N-isopropyl-4-methoxybenzamide 
• 100-07-2 4-methoxy-benzoyl chloride 
• 109-56-8 i-propyl(2-(hydroxy)ethyl)amine 

Downstream Products

• 291299-91-7 N⁶-benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-(N,N-diisopropylamino)-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethoxy]phosphinyl-2'-deoxyadenosine 
• 291299-92-8 N⁴-benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-(N,N-diisopropylamino)-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethoxy]phosphinyl-2'-deoxycytidine 
• 291299-79-1 5'-O-(4,4'-dimethoxytrityl)-3'-O-(N,N-diisopropylamino)-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethoxy]phosphinyl-2'-deoxythymidine 

Relevant articles and documents

Novel phosphate and thiophosphate protecting groups

Novel P(III) bisamidite reagents as phosphorus protecting groups, nucleoside phosphoramidite intermediates, and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared through the protection of one or more int

2-Benzamidoethyl group - A novel type of phosphate protecting group for oligonucleotide synthesis

A number of 5′-O-(4,4′-dimethoxytrityl)thymidine N,N-diisopropylamino phosphoramidites protected at P(III) with derivatives of 2-benzamidoethanol were synthesized and incorporated into synthetic oligonucleotides. Depending on substitution patterns at the