3278-46-4

Basic information

• Product Name: chloropon
• Synonyms: Chloropon [ISO:BSI]; 2,2,3-Trichloropropionic acid; 4-02-00-00759 (Beilstein Handbook Reference); BRN 1756365; Caswell No. 882F; Chloropon; EPA Pesticide Chemical Code 482700; Kyselina 2,2,3-trichlorpropionova; Kyselina 2,2,3-trichlorpropionova [Czech]; Latka 6249; Latka 6249 [Czech]; NSC 32688; Ro 3-1727; TCP (VAN); alpha,alpha,beta-Trichloropropionic acid; Propanoic acid, 2,2,3-trichloro-; Propionic acid, 2,2,3-trichloro-; 2,2,3-trichloropropanoic acid
• CAS NO: 3278-46-4
• Molecular Formula: C₃H₃Cl₃O₂
• Molecular Weight: 177.4137
• EINECS: 221-912-7
• Mol File: 3278-46-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 65.5°C
• Boiling Point: 223.3°C at 760 mmHg
• Flash Point: 88.8°C
• Density: 1.659g/cm³
• Vapor Pressure: 0.0359mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: chloropon(CAS DataBase Reference)
• NIST Chemistry Reference: chloropon(3278-46-4)
• EPA Substance Registry System: chloropon(3278-46-4)

Safety Data

• Hazardous Substances Data: 3278-46-4(Hazardous Substances Data)

Upstream product

• 802294-64-0 propionic acid 
• 64346-45-8 2,3,3,4-tetrachloro-1-butene 
• 598-78-7 (R,S)-2-chloropropionic acid 
• 10151-09-4 (1,1,2,2,3-pentachloro-propyl)-phosphorimidic acid trichloride 
• 4749-35-3 methyl 2,2,3-trichloropropanoate 
• 7789-90-4 2,2,3-trichloro-propionaldehyde 
• 813-74-1 2,2,3-trichloropropionitrile 

Downstream Products

• 99973-91-8 2,2,3-trichloro-propionic acid-[2-(2,4,5-trichloro-phenoxy)-ethyl ester] 

Relevant articles and documents

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Heat Capacities of Activation for the Neutral Hydrolysis of Two Acyl-Activated Esters in Water-Rich 2-n-Butoxyethanol-Water Mixtures. Analysis in Terms of the Pseudo-Phase-Separation Model

The water-catalyzed hydrolysis of p-methoxyphenyl dichloroacetate (1) and 2,2-dichloropropionate (2) in water-rich 2-n-butoxyethanol (2-BE)-H2O exhibits large, positive heat capacities of activation (1, ΔCp = 224 +/- 51 cal mol-1 deg-1; 2, ΔCp = 342 +/- 51 cal mol-1 deg-1; temperature 20-48 deg C) at 2 mol percent of 2-BE (nH2O = 0.98).These positive ΔCp values contrast sharply with the negative ΔCp's found for SN solvolysis reactions in highly aqueous mixed solvents.By use of a pseudothermodynamic approach, the ΔCp values as well as positive heat capacities for transfer (ΔCpΘ,tr) of two model substrates from water to 2-BE-H2O are rationalized within the framework of a pseudo-phase-separation model.Based on previous thermodynamic and other evidence, this model assumes the onset of microphase separation in 2-BE-H2O at about nH2O = 0.98 at 25 deg C.It is shown that temperature-dependent partitioning of the acyl-activated esters between a water-rich and a cosolvent-rich microphase provides an adequate explanation for the observed heat capacity data.The observed ΔCp for solvolysis of tert-butyl chloride in 2-BE-H2O at nH2O = 0.98 is also reconcilable with the proposed theory.