328533-94-4

Basic information

• Product Name: Pyrrolidine, 1-acetyl-2-phenyl- (9CI)
• Synonyms: Pyrrolidine, 1-acetyl-2-phenyl- (9CI)
• CAS NO: 328533-94-4
• Molecular Formula: C12H15NO
• Molecular Weight: 0
• Mol File: 328533-94-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyrrolidine, 1-acetyl-2-phenyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolidine, 1-acetyl-2-phenyl- (9CI)(328533-94-4)
• EPA Substance Registry System: Pyrrolidine, 1-acetyl-2-phenyl- (9CI)(328533-94-4)

Safety Data

• Hazardous Substances Data: 328533-94-4(Hazardous Substances Data)

Relevant articles and documents

Tf2O-Promoted Intramolecular Schmidt Reaction of the ω-Azido Carboxylic Acids

A designed Tf2O-promoted intramolecular Schmidt reaction of 2-substituted ω-azido carboxylic acids was demonstrated. Tf2O was used as an activation reagent for the carboxylic acid, and ω-azido anhydride was in situ generated, releasing a molecular TfOH, which acted as an acid promoter for the Schmidt process. A series of 2-substituted pyrrolidines was produced and acetylated for better purification. The strategy was also efficient for conversion of a 4-substituted ω-azido carboxylic acid to the tricyclic lactam.