3288-04-8

Basic information

• Product Name: 2-METHOXYPHENYL ISOTHIOCYANATE
• Synonyms: Benzene, 1-isothiocyanato-2-methoxy-;ISOTHIOCYANIC ACID 2-METHOXYPHENYL ESTER;1-ISOTHIOCYANATO-2-METHOXY-BENZENE;2-METHOXYPHENYL ISOTHIOCYANATE;O-METHOXYPHENYL ISOTHIOCYANATE;o-Anisyl isothiocyanate;2-Methoxy-1-isothiocyanatobenzene;2-Methoxyphenyl isothiocyanate,99%
• CAS NO: 3288-04-8
• Molecular Formula: C₈H₇NOS
• Molecular Weight: 165.21
• EINECS: 626-109-9
• Product Categories: Organic Building Blocks;Sulfur Compounds;Thiocyanates/Isothiocyanates
• Mol File: 3288-04-8.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 264-266 °C
• Flash Point: >110°C
• Appearance: Clear light yellow/Liquid
• Density: 1.19
• Vapor Pressure: 0.0154mmHg at 25°C
• Refractive Index: 1.6433-1.6453
• Water Solubility: Reacts with water.
• Sensitive: Moisture Sensitive
• BRN: 638293
• CAS DataBase Reference: 2-METHOXYPHENYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXYPHENYL ISOTHIOCYANATE(3288-04-8)
• EPA Substance Registry System: 2-METHOXYPHENYL ISOTHIOCYANATE(3288-04-8)

Safety Data

• Hazard Codes: T,C
• Statements: 36/37/38-23/24/25-36/37-34
• Safety Statements: 45-38-36/37/39-28A-26-28-27
• RIDADR: 2922
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 3288-04-8(Hazardous Substances Data)

Usage

Description

2-METHOXYPHENYL ISOTHIOCYANATE, also known as 2-Methoxyphenyl Mustard Oil, is an organic compound with the chemical formula C8H7NOS. It is a clear light yellow liquid that has been investigated through IR and Raman spectral measurements for liquid samples. 2-METHOXYPHENYL ISOTHIOCYANATE is known for its unique chemical properties and potential applications in various industries.

Uses

Used in Pharmaceutical Industry:
2-METHOXYPHENYL ISOTHIOCYANATE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its application reason lies in its unique chemical structure, which can be modified and utilized to create new drugs with potential therapeutic effects.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-METHOXYPHENYL ISOTHIOCYANATE serves as a valuable building block for the creation of a wide range of organic compounds. Its application reason is due to its reactive isothiocyanate group, which can easily undergo various chemical reactions to form new molecules with different properties and applications.
Used in Research and Development:
2-METHOXYPHENYL ISOTHIOCYANATE is used as a research compound for studying its chemical properties, reactivity, and potential applications in various fields. The application reason is to gain a deeper understanding of its behavior and to explore new ways to utilize this compound in the development of new products and technologies.
Used in Agrochemical Industry:
2-METHOXYPHENYL ISOTHIOCYANATE can be used as a starting material for the development of new agrochemicals, such as pesticides and herbicides. Its application reason is based on its potential to be modified and combined with other compounds to create effective and environmentally friendly solutions for agricultural challenges.

InChI:InChI=1/C8H7NOS/c1-10-8-5-3-2-4-7(8)9-6-11/h2-5H,1H3

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 6160-65-2 1,1'-Thiocarbonyldiimidazole 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 590-28-3 potassium cyanate 
• 56676-49-4 2-mercapto-3-(o-methoxyphenyl)-4-thiazolidone 
• 1075256-86-8 3-(2-methoxyphenyl)-5-(2-oxo-2-phenylethyl)-2-thioxo-1,3-thiazolidin-4-one 
• 75-15-0 carbon disulfide 
• 53662-51-4 (2-methoxy-phenyl)-dithiocarbamic acid ; compound with triethylamine 
• 248279-10-9 N,N'-bis-(2-methoxy-phenyl)-S-methyl-isothiourea 
• 110837-92-8 C₂₆H₂₅AsN₂O₂ 
• 74467-01-9 2-methoxybenzohydroximoyl chloride 
• 463-71-8 thiophosgene 
• 854902-49-1 (2-methoxy-phenyl)-dithiocarbamic acid methyl ester 
• 1226-64-8 1,3-bis-(2-methoxy-phenyl)-thiourea 

Downstream Products

• 103151-15-1 (4,5-dihydro-thiazol-2-yl)-(2-methoxy-phenyl)-amine 
• 133168-47-5 N-(2-methoxyphenyl)piperidine-1-carbothioamide 
• 1226-64-8 1,3-bis-(2-methoxy-phenyl)-thiourea 
• 516458-14-3 1-benzoyl-4-(2-methoxy-phenyl)-thiosemicarbazide 
• 108838-82-0 N-[[(2-methoxyphenyl)amino]thioxomethyl]-4-methylphenylsulfonamide 
• 2741-07-3 N-ethyl-N'-(2-methoxy-phenyl)-thiourea 
• 1219-02-9 N-(o-methoxyphenyl)-N'-phenylthiourea 
• 905481-43-8 hydrazine-N,N'-bis-carbothioic acid di-o-anisidide 
• 859785-61-8 N'-isopropyl-N'''-(2-methoxy-phenyl)-N,N''-p-phenylene-bis-thiourea 
• 857977-58-3 N'-butyl-N'''-(2-methoxy-phenyl)-N,N''-p-phenylene-bis-thiourea 
• 27779-18-6 (5,6-dihydro-4H-[1,3]thiazin-2-yl)-(2-methoxy-phenyl)-amine 
• 135-62-6 Naphthol AS-OL 
• 109868-54-4 3-(2-methoxy-phenylthiocarbamoyl)-carbazic acid ethyl ester 
• 40207-02-1 4-(o-methoxyphenyl)thiosemicarbazide 

Relevant articles and documents

Microwave mediated synthesis of 2-aminooxazoles

A microwave mediated synthesis of 2-aminooxazoles at 150 °C was developed, providing products with a variety of functional groups. The reaction takes 5 min and provides product with a simple precipitation at moderate to good yields without the need for recrystallization or flash chromatography.

Direct, Microwave-Assisted Synthesis of Isothiocyanates

A microwave-assisted desulfuration of readily available dithiocarbamates, formed in situ from primary amines, leading to target isothiocyanates has been developed. This efficient protocol provides a rapid, environmentally benign route to aliphatic and aromatic isothiocyanates.

CYCLOALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures:(I) (II) where the definitions of the variables are provided herein.