329191-57-3

Basic information

• Product Name: (2S,4S)-N^α-Cbz-4-aminoproline benzyl ester
• Synonyms: (2S,4S)-N^α-Cbz-4-aminoproline benzyl ester
• CAS NO: 329191-57-3
• Molecular Weight: 354.406
• Mol File: 329191-57-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,4S)-N^α-Cbz-4-aminoproline benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-N^α-Cbz-4-aminoproline benzyl ester(329191-57-3)
• EPA Substance Registry System: (2S,4S)-N^α-Cbz-4-aminoproline benzyl ester(329191-57-3)

Safety Data

• Hazardous Substances Data: 329191-57-3(Hazardous Substances Data)

Usage

Description

(2S,4S)-N^α-Cbz-4-aminoproline benzyl ester is a chemical compound derived from proline, an essential amino acid. It is specifically configured with an N-terminus protected by a carbobenzyloxy group (Cbz) and features an ester bond with a benzyl group. This unique structure facilitates the controlled incorporation of the compound into peptide chains, making it a valuable building block in the synthesis of various peptides and proteins.

Uses

Used in Pharmaceutical Industry:
(2S,4S)-N^α-Cbz-4-aminoproline benzyl ester is used as a key component in the production of peptide-based drugs. Its controlled addition into peptide chains allows for the creation of specific drug molecules with targeted therapeutic effects.
Used in Research:
In research settings, (2S,4S)-N^α-Cbz-4-aminoproline benzyl ester is utilized for the synthesis of custom peptides and proteins. This enables scientists to design and create novel peptide and protein structures for a wide range of applications, including therapeutic development, diagnostic tools, and fundamental biological studies.

Upstream product

• 13504-85-3 (2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid 
• 100-51-6 benzyl alcohol 
• 159551-87-8 (2S,4R)-N^α-Cbz-4-[(p-toluenesulfonyl)oxy]proline benzyl ester 
• 13500-53-3 N-benzyloxycarbonyl-(2S,4R)-4-hydroxyproline benzyl ester 
• 329191-55-1 (2S,4S)-N^α-Cbz-4-azidoproline benzyl ester 
• 81464-46-2 (2S,4S)-4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-pyrrolidine-1,2-dicarboxylic acid dibenzyl ester 

Downstream Products

• 1393739-69-9 6(I)-[N'-(2S,4S)-1,2-dibenzyloxycarbonylpyrrolidin-4-yl]aminocarbonylethylcarbonylamino-6(I)-deoxy-β-cyclodextrin 
• 1000312-50-4 (2S,4S)-4-acetamido-1,2-dibenzyloxycarbonylpyrrolidine 
• 1352655-90-3 C₂₆H₂₉N₄O₅⁽¹⁺⁾*Cl^(1-) 
• 1352655-92-5 C₂F₆NO₄S₂^(1-)*C₂₆H₂₉N₄O₅⁽¹⁺⁾ 
• 1352655-89-0 N-benzyloxycarbonyl-(2S,4S)-4-(2-chloroacetamido)-proline benzyl ester 
• 1146289-56-6 dibenzyl (2S,4S)-4-(4-methylphenylsulfonamido)pyrrolidine-1,2-dicarboxylate 
• 221352-74-5 (2S,4S)-1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine2-carboxylic acid 
• 1279034-78-4 (2S,4S)-4-tert-Butoxycarbonylamino-pyrrolidine-2-carboxylic acid 
• 853063-23-7 (2S,4S)-N^α-Cbz-4-N-Boc-aminoproline benzyl ester 
• 329191-59-5 (2S,4S)-N^α-Cbz-4-N,N'-di-Boc-guanidinoproline benzyl ester 

Relevant articles and documents

Asymmetric aldol reaction using immobilized proline on mesoporous support

The aldol reaction of hydroxyacetone with different aldehydes using immobilized proline on a mesoporous support, assisted by heat and microwaves, has been explored. It was found that heterogenized L-proline on MCM-41 catalyzed aldol reactions in both hydr