329897-76-9

Basic information

• Product Name: 4-amino-1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-5-hydroxymethyl-1H-pyrimidin-2-one
• CAS NO: 329897-76-9
• Molecular Weight: 511.65
• Mol File: 329897-76-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-amino-1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-5-hydroxymethyl-1H-pyrimidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-5-hydroxymethyl-1H-pyrimidin-2-one(329897-76-9)
• EPA Substance Registry System: 4-amino-1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-5-hydroxymethyl-1H-pyrimidin-2-one(329897-76-9)

Safety Data

• Hazardous Substances Data: 329897-76-9(Hazardous Substances Data)

Upstream product

• 329897-75-8 4-amino-1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidin-2-one 
• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 
• 3180-76-5 2',3',5'-tri-O-benzoyluridine 
• 59237-68-2 2',3',5'-tri-O-benzoyl-5-methylcytidine 
• 163496-05-7 C₃₃H₂₇N₅O₈ 
• 7288-28-0 2,4-bis(trimethylsiloxy)-5-methylpyrimidine 
• 2140-61-6 5-methylcytidine 

Downstream Products

• 329897-77-0 4-Amino-1-[(2R,3R,4S,5R)-5-(tert-butyl-diphenyl-silanyloxymethyl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidine-5-carbaldehyde 
• 148608-53-1 5-formylcytidine 

Relevant articles and documents

Facile methods for the synthesis of 5-formylcytidine

5′-O-Protected 5-methylcytidine 3 was oxidized with Na2S2O8 to give a mixture of the corresponding 5-(hydroxymethyl)- and 5-formylcytidine derivatives, 4 and 5. The hydroxymethyl group of 4 was further oxidized to a formyl group by treatment with ceric(IV) ammonium nitrate (CAN). Alternatively, 2′,3′,5′-O-protected 5-(hydroxymethyl)cytidine 10 was directly oxidized with CAN to give the desired 5-formylcytidine derivative 11. After removal of the protecting groups in each intermediate, 5-formylcytidine (6) was obtained in good yield.