33069-21-5

Basic information

• Product Name: 6β-phenoxyacetamidopenicillanic acid 1β-sulfoxide
• Synonyms: 6β-phenoxyacetamidopenicillanic acid 1β-sulfoxide
• CAS NO: 33069-21-5
• Molecular Weight: 366.395
• Mol File: 33069-21-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 6β-phenoxyacetamidopenicillanic acid 1β-sulfoxide(CAS DataBase Reference)
• NIST Chemistry Reference: 6β-phenoxyacetamidopenicillanic acid 1β-sulfoxide(33069-21-5)
• EPA Substance Registry System: 6β-phenoxyacetamidopenicillanic acid 1β-sulfoxide(33069-21-5)

Safety Data

• Hazardous Substances Data: 33069-21-5(Hazardous Substances Data)

Upstream product

• 87-08-1 penicilin V 
• 10213-10-2 sodium tungstate (VI) dihydrate 

Downstream Products

• 380412-94-2 3-methyl-2-((1R)-7-oxo-3-phenoxymethyl-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-but-2-enoic acid methyl ester 
• 35500-85-7 (1R)-3ξ-methyl-2-phenoxyacetyl-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]heptan-7-one 
• 35500-75-5 (1R)-3-phenoxymethyl-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-7-one 
• 35500-84-6 3-methyl-2-((1R)-3ξ-methyl-7-oxo-2-phenoxyacetyl-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-6-yl)-but-2-enoic acid methyl ester 
• 41230-47-1 [3,3,8,8-tetramethyl-1-oxo-6-(2-phenoxy-acetylamino)-oxazolo[4,3-c][1,4]thiazin-8a-yl]-phosphonic acid diethyl ester 
• 41230-49-3 N-(8a-chloromethyl-3,3,8,8-tetramethyl-1-oxo-8,8a-dihydro-1H-oxazolo[4,3-c][1,4]thiazin-6-yl)-2-phenoxy-acetamide 
• 40579-22-4 (2S,3S)-3-Iodo-3-methyl-8-oxo-7-(2-phenoxy-acetylamino)-5-thia-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid methyl ester 
• 59203-76-8 (R)-3-methyl-2-((1R)-7-oxo-3-phenoxymethyl-(1rH,5cH)-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-but-3-enoic acid methyl ester 
• 131830-22-3 methyl 6β-phenoxythioacetamidopenicillanate 1β-sulfoxide 
• 59207-15-7 methyl 2-(3-phenoxymethyl-4,5-dithia-2,7-diazabicyclo<4.2.0>oct-2-en-8-one-7-yl)-3-methylbut-3-enoate 
• 131830-23-4 6β-phenoxythioacetamidopenicillanic acid 1β-sulfoxide 
• 41327-59-7 3,3,8,8-tetramethyl-1-oxo-6-(2-phenoxy-acetylamino)-3,8-dihydro-1H-oxazolo[4,3-c][1,4]thiazinylium; chloride 
• 49780-36-1 (R)-2-[(2R)-2r-benzothiazol-2-yldisulfanyl-4-oxo-3c-(2-phenoxy-acetylamino)-azetidin-1-yl]-3-methyl-but-3-enoic acid 
• 73171-16-1 (4S)-5,5-dimethyl-1t-oxo-2t-((R)-5-oxo-2-phenoxymethyl-4,5-dihydro-oxazol-4-yl)-3-(N-phenoxyacetyl-glycyl)-1λ⁴-thiazolidine-4r-carboxylic acid 

Relevant articles and documents

A simple and efficient preparation of penicillin V β-sulfoxide

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A mild and convenient synthesis of penicillin and cephalosporin sulfoxides

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Process for the ring expansion of penicillins to cephalosporin compounds

A process for producing a 2-cephem or 3-cephem derivative compound of the formula: SPC1 Wherein R1 represents a substituted or unsubstituted amino radical and R4 represents hydrogen or a radical selected from the group consisting of carboxy, protected carboxy, ester, acid amide, acid anhydride, acid halide, acid azide and carboxy salt, and the dotted line indicates the alternate bond structure providing 3-cephem or 2-cephem, which comprises: Reacting a halogenated derivative selected from the group consisting of a halogenated penam derivative having the formula: SPC2 A halogenated cepham derivative of the formula: SPC3 Wherein X represents a halogen atom, R3 represents a radical selected from the group consisting of carboxy, protected carboxy, ester, acid amide, acid anhydride, acid halide, acid azide and carboxy salt, and R1 is as defined above, or mixtures thereof with a dehydrohalogenoic acid reagent.