33119-65-2

Basic information

• Product Name: 4-Phenyl-oxazol-2-ylaMine
• Synonyms: 4-Phenyl-oxazol-2-ylaMine;4-Phenyloxazol-2-aMine;4-Phenyl-2-oxazolamine;4-phenyl-1,3-oxazol-2-amine;2-amino-4-phenyloxazole
• CAS NO: 33119-65-2
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.17262
• Mol File: 33119-65-2.mol
• Article Data: 8

Chemical Properties

• Melting Point: 221-223 °C
• Boiling Point: 130 °C(Press: 0.1 Torr)
• Appearance: /
• Density: 1.204±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 4.73±0.10(Predicted)
• CAS DataBase Reference: 4-Phenyl-oxazol-2-ylaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Phenyl-oxazol-2-ylaMine(33119-65-2)
• EPA Substance Registry System: 4-Phenyl-oxazol-2-ylaMine(33119-65-2)

Safety Data

• Hazardous Substances Data: 33119-65-2(Hazardous Substances Data)

Usage

General Description

4-Phenyl-oxazol-2-ylaMine is a chemical compound with the molecular formula C13H10N2O. It is an organic compound that belongs to the class of oxazole derivatives. 4-Phenyl-oxazol-2-ylaMine contains a phenyl group attached to an oxazole ring, which consists of both nitrogen and oxygen atoms. 4-Phenyl-oxazol-2-ylaMine has potential applications in drug discovery and development due to its pharmacological properties. It may also have uses in the field of materials science and organic synthesis. However, as with any chemical compound, careful handling and proper safety precautions should be followed when working with 4-Phenyl-oxazol-2-ylaMine.

Upstream product

• 420-04-2 CYANAMID 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 64-17-5 ethanol 
• 70-11-1 α-bromoacetophenone 
• 2243-35-8 2-acetoxyacetophenone 
• 57-13-6 urea 

Downstream Products

• 115754-38-6 [1-(4-Chloro-phenyl)-meth-(E)-ylidene]-(4-phenyl-oxazol-2-yl)-amine 
• 115754-37-5 [1-(4-Nitro-phenyl)-meth-(E)-ylidene]-(4-phenyl-oxazol-2-yl)-amine 
• 115754-36-4 [1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-(4-phenyl-oxazol-2-yl)-amine 
• 115754-39-7 2-{[(E)-4-Phenyl-oxazol-2-ylimino]-methyl}-phenol 
• 97600-14-1 2-amino-N,4-diphenyloxazole-5-carbothioamide 
• 97600-13-0 2-amino-N-methyl-4-phenyloxazole-5-carbothioamide 
• 115754-40-0 [1-(4-Dimethylamino-phenyl)-meth-(E)-ylidene]-(4-phenyl-oxazol-2-yl)-amine 
• 1345732-15-1 4'-phenyl-N-(4-phenyloxazol-2-yl)-1'H-pyrrole-3'-carboxamide 
• 1345732-24-2 4',5'-dihydro-4'-phenyl-N-(4-phenyloxazol-2-yl)-1'H-pyrazole-3'-carboxamide 
• 1345732-33-3 4'-phenyl-N-(4-phenyloxazol-2-yl)-1'H-pyrazole-3'-carboxamide 
• 1345732-08-2 (E)-N-(4-phenyloxazol-2-yl)cinnamamide 

Relevant articles and documents

Synthesis and biological evaluation of sulfonamidooxazoles and β-keto sulfones: Selective inhibitors of 11β-hydroxysteroid dehydrogenase type I

The design, synthesis, and biological evaluation of arylsulfonamidooxazoles as 11β-HSD1 inhibitors and the serendipitous discovery of β-keto sulfones as potent 11β-HSD1 inhibitors are described here. These two classes of compounds are not active against 11β-HSD2 and therefore may have significant therapeutic potential for metabolic syndrome, type 2 diabetes and related metabolic dysfunctions.

Synthesis, Characterization, and Antioxidant Activity of a New Class of Amido linked Azolyl Thiophenes

A new class of amido linked azolyl thiophenes was prepared from the synthetic intermediates azolyl amines and 5-chlorothiophene-2-carbonyl chloride adopting conventional and ultrasonication methodologies. It was observed that the reaction took place in shorter reaction times with higher yields under ultrasonication. The structures of the synthesized compounds were characterized by spectral parameters and also tested for antioxidant activity. Among all the tested compounds, methoxy substituted oxazolyl thiophene carboxamide (8c) displayed promising antioxidant activity. Besides, the electron donating groups on the phenyl ring enhanced the antioxidant activity when compared with the electron withdrawing groups.

HEPATITIS B CORE PROTEIN ALLOSTERIC MODULATORS

ABSTRACT The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.