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331729-57-8

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331729-57-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 331729-57-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,1,7,2 and 9 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 331729-57:
(8*3)+(7*3)+(6*1)+(5*7)+(4*2)+(3*9)+(2*5)+(1*7)=138
138 % 10 = 8
So 331729-57-8 is a valid CAS Registry Number.

331729-57-8Relevant articles and documents

Discovery of 5-substituent-N-arylbenzamide derivatives as potent, selective and orally bioavailable LRRK2 inhibitors

Ding, Xiao,Dai, Xuedong,Long, Kai,Peng, Cheng,Andreotti, Daniele,Bamborough, Paul,Eatherton, Andrew J.,Edge, Colin,Jandu, Karamjit S.,Nichols, Paula L.,Philps, Oliver J.,Stasi, Luigi Piero,Wan, Zehong,Xiang, Jia-Ning,Dong, Kelly,Dossang, Pamela,Ho, Ming-Hsun,Li, Yi,Mensah, Lucy,Guan, Xiaoming,Reith, Alastair D.,Ren, Feng

supporting information, p. 4034 - 4038 (2017/08/23)

Leucine-rich repeat kinase 2 (LRRK2) has been suggested as a potential therapeutic target for Parkinson's disease. Herein we report the discovery of 5-substituent-N-arylbenzamide derivatives as novel LRRK2 inhibitors. Extensive SAR study led to the discovery of compounds 8e, which demonstrated potent LRRK2 inhibition activity, high selectivity across the kinome, good brain exposure, and high oral bioavailability.

MITOTIC KINESIN INHIBITORS

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Page/Page column 45-46, (2008/06/13)

The present invention relates to tricyclic pyrazoles that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions whic

AZEPANES AND THEIR RING HOMOLOGUES HAVING PROTEIN KINASE INHIBITING ACTIVITY

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, (2008/06/13)

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