331866-82-1

Basic information

• Product Name: (R)-3-((S)-2-Benzyloxycarbonylamino-5-tert-butoxycarbonylamino-pentanoylamino)-hexadecanoic acid benzotriazol-1-yl ester
• CAS NO: 331866-82-1
• Molecular Weight: 736.952
• Mol File: 331866-82-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-((S)-2-Benzyloxycarbonylamino-5-tert-butoxycarbonylamino-pentanoylamino)-hexadecanoic acid benzotriazol-1-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-((S)-2-Benzyloxycarbonylamino-5-tert-butoxycarbonylamino-pentanoylamino)-hexadecanoic acid benzotriazol-1-yl ester(331866-82-1)
• EPA Substance Registry System: (R)-3-((S)-2-Benzyloxycarbonylamino-5-tert-butoxycarbonylamino-pentanoylamino)-hexadecanoic acid benzotriazol-1-yl ester(331866-82-1)

Safety Data

• Hazardous Substances Data: 331866-82-1(Hazardous Substances Data)

Upstream product

• 331866-81-0 (R)-3-((S)-2-Benzyloxycarbonylamino-5-tert-butoxycarbonylamino-pentanoylamino)-hexadecanoic acid methyl ester 
• 331866-79-6 (R)-3-[Benzyl-((R)-1-phenyl-ethyl)-amino]-hexadecanoic acid methyl ester 
• 331866-80-9 (R)-3-Amino-hexadecanoic acid methyl ester 
• 124-25-4 myristylaldehyde 
• 2825-81-2 methyl hexadec-trans-2-enoate 

Relevant articles and documents

An expedient synthesis of the amide analog of the potent antifungal lipopeptidolactone FR901469

An expedient synthesis of the lactam analog (20) of the 40-membered lipopeptidolactone antifungal antibiotic, FR901469 (1), is described. The key steps in this synthesis are a novel biotransformation of the natural product to produce the highly versatile linear peptide building block 3, and efficient formation of the 40-membered ring by macrolactamization under high-dilution conditions.