3319-03-7 Usage
Description
α-(Dimethylamino)acetophenone is an organic compound that serves as an intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its chemical structure, which includes a dimethylamino group attached to an acetophenone molecule.
Uses
Used in Pharmaceutical Industry:
α-(Dimethylamino)acetophenone is used as an intermediate in the synthesis of 1-(Dimethylamino)-2-phenyl-2-butanyl 3,4,5-trimethoxybenzoate (D493076), which is a degradation product of trimebutine maleate and an impurity of trimebutine. Trimebutine is an opioid receptor agonist and an antispasmodic agent, utilized for the treatment of acute and chronic abdominal pain. Its role in the synthesis process is crucial for the development of these medications, contributing to their effectiveness in managing pain and discomfort.
Check Digit Verification of cas no
The CAS Registry Mumber 3319-03-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,1 and 9 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 3319-03:
(6*3)+(5*3)+(4*1)+(3*9)+(2*0)+(1*3)=67
67 % 10 = 7
So 3319-03-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO/c1-11(2)8-10(12)9-6-4-3-5-7-9/h3-7H,8H2,1-2H3
3319-03-7Relevant articles and documents
Synthesis of 1-organyl-1-(trimethylsiloxy)-2-(dimethylamino)ethenes and new hypervalent silicon compounds based thereon
Gostevskii,Albanov,Vashchenko,Smirnov
, p. 1385 - 1389 (2016)
1-Organyl-1-(trimethylsiloxy)-2-(dimethylamino)ethenes were synthesized for the first time, and their reactions with trichloro(methyl)silane and trifluoro(phenyl)silane afforded silicon bis-chelates, methylbis-[2-(dimethylamino)-1-(organyl)ethenolato-N,O]
Superelectrophilic chemistry of amino-nitriles and related substrates
Raja, Erum K.,Klumpp, Douglas A.
experimental part, p. 4494 - 4497 (2011/07/08)
The superacid-promoted Houben/Hoesch reactions of amino-nitriles and related compounds have been studied. The nitriles form dicationic electrophiles and react with benzene in fair to good yields (12-95%). The intermediate iminium ions may also be reduced to the benzylic amines by NaBH4 or H 2.
Asymmetric synthesis of α-N,N-dialkylamino alcohols by transfer hydrogenation of N,N-dialkylamino ketones
Kosmalski, Tomasz
experimental part, p. 717 - 721 (2011/05/14)
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