33192-00-6

Basic information

• Product Name: Ethanone, 1-(4-chlorophenyl)-2-(phenylthio)-
• Synonyms: 1-(4-chloro-phenyl)-2-phenylsulfanyl-ethanone;α-(phenylthio)-4-chloroacetophenone;α-phenylthio-p-chloroacetophenone;1-(4-chlorophenyl)-2-(phenylthio)ethanone;1-(4-Chlor-phenyl)-2-phenylmercapto-aethanon;α-(Phenylthio)-p-chloroacetophnone
• CAS NO: 33192-00-6
• Molecular Formula: C14H11ClOS
• Molecular Weight: 262.76
• Mol File: 33192-00-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(4-chlorophenyl)-2-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-chlorophenyl)-2-(phenylthio)-(33192-00-6)
• EPA Substance Registry System: Ethanone, 1-(4-chlorophenyl)-2-(phenylthio)-(33192-00-6)

Safety Data

• Hazardous Substances Data: 33192-00-6(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(4-chlorophenyl)-2-(phenylthio)-, also known as ketone or thioether, is a compound consisting of a ketone functional group attached to a benzene ring with a chloro substituent on the para position and a sulfur atom on the ortho position of another benzene ring. This chemical structure gives it unique properties and potential applications in various fields such as pharmaceuticals, agrochemicals, and materials science. It may exhibit biological activity due to the presence of the substituted benzene rings, making it a potential candidate for further research in drug discovery. Additionally, the thioether group can impart specific chemical and physical properties that may be of interest for industrial uses.

Upstream product

• 99-91-2 para-chloroacetophenone 
• 108-98-5 thiophenol 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 104-88-1 4-chlorobenzaldehyde 
• 111198-03-9 1-((phenylthio)methyl)-1H-benzo[d][1,2,3]triazole 
• 930-69-8 sodium thiophenolate 
• 96928-08-4 2-[2-(4-Chloro-phenyl)-2-oxo-ethylsulfanyl]-1-methyl-4,6-diphenyl-pyridinium; bromide 

Downstream Products

• 1235497-46-7 6-(4-chlorophenyl)-4-[4-(dimethylamino)phenyl]-2-ethoxy-5-(phenylsulfanyl)nicotinonitrile 
• 69602-25-1 ((4-chlorophenyl)ethynyl)(phenyl)sulfane 
• 1380501-87-0 4-(5-(4-chlorophenyl)furan-3-yl)butyl pivalate 
• 1380501-74-5 2-(4-chlorophenyl)-4-hexylfuran 
• 1363159-06-1 (S)-1-(4-chlorophenyl)-2-(phenylthio)ethanol 
• 1260255-29-5 C₂₈H₂₂Cl₂N₂S₂ 
• 63216-03-5 1-(4-Chloro-phenyl)-2-(4-methoxy-phenyl)-2-phenylsulfanyl-ethanone 
• 153235-59-7 6-(4-Chloro-phenyl)-3-phenyl-7-phenylsulfanyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine 
• 153235-57-5 6-(4-Chloro-phenyl)-3-methyl-7-phenylsulfanyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine 
• 58936-71-3 ω-Phenylsulfinyl-p-chloracetophenon 

Relevant articles and documents

Catalytic Asymmetric [4 + 1] Annulation of Sulfur Ylides with Copper-Allenylidene Intermediates

The first copper-catalyzed asymmetric decarboxylative [4 + 1] cycloaddition of propargylic carbamates and sulfur ylides was successfully developed. This strategy led to a series of chiral indolines with synthetically flexible alkyne groups in good yields and with high enantio- and diastereoselectivities (up to 99% yield, 98% ee, and >95:5 dr). A possible mechanism and stereoinduction mode with copper-allenylidenes were proposed as the possible dipolar intermediate.

Gold-catalyzed carbene transfer to alkynes: Access to 2,4-disubstituted furans

Furans of gold: The first example of a gold-catalyzed intermolecular addition of carbon ylides to terminal alkynes is reported (see scheme; DCE=dichloroethane, Tf=trifluoromethanesulfonyl). Subsequent intramolecular trapping of the generated gold carbene completes a formal [3+2] cycloaddition, which represents a novel synthesis of 2,4-disubstituted furans. Copyright

Pyrazole derivatives from azines of substituted phenacyl aryl/cyclohexyl sulfides and their antimycobacterial activity

Azines derived from substituted phenacyl aryl/cyclohexyl sulfide on treatment with excess phosphorous oxychloride in N,N-dimethylformamide have been found to yield two isomeric pyrazoles in each case. A plausible mechanism has been suggested for the forma