331943-78-3

Basic information

• Product Name: 2-bromo-5-methoxymethyl-1,3-bis[(2-trimethylsilylethoxy)methoxy]-benzene
• CAS NO: 331943-78-3
• Molecular Weight: 493.586
• Mol File: 331943-78-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-bromo-5-methoxymethyl-1,3-bis[(2-trimethylsilylethoxy)methoxy]-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-5-methoxymethyl-1,3-bis[(2-trimethylsilylethoxy)methoxy]-benzene(331943-78-3)
• EPA Substance Registry System: 2-bromo-5-methoxymethyl-1,3-bis[(2-trimethylsilylethoxy)methoxy]-benzene(331943-78-3)

Safety Data

• Hazardous Substances Data: 331943-78-3(Hazardous Substances Data)

Upstream product

• 99-10-5 3,5-Dihydroxybenzoic acid 
• 16534-12-6 3,5-dihydroxy-4-bromobenzoic acid 
• 34126-16-4 4-bromo-3,5-dihydroxy-benzoic acid methyl ester 
• 331943-74-9 methyl 4-bromo-3,5-bis[(2-trimethylsilylethoxy)methoxy]benzoate 
• 331943-76-1 [4-bromo-3,5-bis-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-methanol 
• 74-88-4 methyl iodide 

Relevant articles and documents

Synthesis of the racemate of the stereoisomer at C-6a of BE-40644, a bioactive metabolite of Actinoplanes sp. with a sesquiterpene-substituted p-benzoquinone structure.

BE-40644 is a tetracyclic metabolite of Actinoplanes sp. A 40644 possessing a sesquiterpene-substituted p-benzoquinone structure with cis-fused B/C ring stereochemistry that inhibits the human thioredoxin system as the well as the growth of several cancer cell lines. Its B/C trans-fused stereoisomer at C-6a was synthesized as a racemate starting from geranylacetone and 3,5-dihydroxybenzoic acid.