3320-35-2Relevant articles and documents
[PF6]2 As catalyst for the meyer-schuster rearrangement of arylpropargylic alcohols under mild conditions
Talavera, María,Bravo, Jorge,Gonsalvi, Luca,Peruzzini, Maurizio,Zuccaccia, Cristiano,Bola?o, Sandra
, p. 6268 - 6274 (2014)
The novel iridium complex [IrCpNCMe2PPh2Me][PF6]2 I efficiently catalyzed the Meyer-Schuster rearrangement of selected arylpropargylic alcohols into α,β-unsaturated aldehydes under mild conditions and without the need of a co-catalyst. A mechanism involving a hydroxy alkenylcarbene intermediate is proposed. [IrCpNCMe2PPh2Me][PF6]2 efficiently catalyzes the rearrangement of propargylic alcohols into α,β-unsaturated aldehydes under mild conditions and without the need of a co-catalyst.
Silver sequestration of halides for the activation of Pd(OAc)2 catalyzed Mizoroki-Heck reaction of 1,1 and 1,2 - Disubstituted alkenes
Bangar, Pronnoy G.,Jawalkar, Priyanka R.,Dumbre, Swapnil R.,Patil, Dharmaraj J.,Iyer, Suresh
, (2017/11/23)
A ligand free catalytic system consisting of Pd(OAc)2 (cat) and stoichiometric quantities of silver salts, AgOAc or AgBF4, exhibit high efficiency in the Mizoroki-Heck arylation, transforming aryl iodides and 1,1 as well as 1,2 disubstituted alkenes into 1,1,2 – trisubstituted aryl alkenes in excellent yields in very short reaction times.
A Weinreb Amide Based Building Block for Convenient Access to β,β-Diarylacroleins: Synthesis of 3-Arylindanones
Tiwari, Praveen Kumar,Aidhen, Indrapal Singh
, p. 2637 - 2646 (2016/06/08)
Towards the synthesis of symmetrical and unsymmetrical β,β-diarylacroleins for assembling diarylmethine fragments present in biologically important molecules, we have developed a new Weinreb amide (WA) based building block, derived from propiolic acid. The WA functionality present in this compound allowed the sequential addition of various arylmagnesium bromide reagents in a controlled manner. The developed methodology for the access to β,β-diarylacroleins has been utilised for the synthesis of biologically important 3-arylindanone molecules. Synthesis of both symmetrical and unsymmetrical β,β-diarylacrolein and diarylmethine fragments, have been achieved via easily accessible and hitherto unknown Weinreb Amide (WA) based building block 11. The WA functionality allowed the sequential addition of nucleophiles such as arylmagnesium bromide in a controlled manner, which has enabled the synthesis of an important 3-arylindanone molecule.
