332081-60-4 Usage
General Description
2-(benzyl-o-tolyl-amino)-N,N-diethyl-benzamide, commonly known as diethylaminobenzamide or DEAB, is a synthetic organic compound with a complex chemical structure. It is a type of benzamide and contains substituents such as benzyl and o-tolyl amino groups. DEAB is commonly used as a reagent in chemical and biological research, particularly in the field of cancer biology, where it has been found to inhibit the function of aldehyde dehydrogenase enzymes. This inhibition can have significant effects on cell proliferation and differentiation, making DEAB a valuable tool in understanding the processes of tumorigenesis and development. Additionally, DEAB has been investigated for its potential as a drug candidate for the treatment of certain types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 332081-60-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,2,0,8 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 332081-60:
(8*3)+(7*3)+(6*2)+(5*0)+(4*8)+(3*1)+(2*6)+(1*0)=104
104 % 10 = 4
So 332081-60-4 is a valid CAS Registry Number.
332081-60-4Relevant articles and documents
New synthesis of oxcarbazepine via remote metalation of protected N-o-tolyl-anthranilamide derivatives
Lohse, Olivier,Beutler, Ulrich,Fünfschilling, Peter,Furet, Pascal,France, Julien,Kaufmann, Daniel,Penn, Gerhard,Zaugg, Werner
, p. 385 - 389 (2007/10/03)
Benzyl and allyl protected N-o-tolyl-anthranilamides were efficiently prepared by Buchwald-Hartwig C-N cross coupling reactions, followed by protection of the amino group. Under directed remote metalation conditions, protected dibenzoazepinones were obtained in good yields. Deprotection of the amine and conversion to an urea furnished a new and efficient synthesis of the antiepileptic drug Trileptal.