33252-62-9

Basic information

• Product Name: 2-Methoxy-3-Nitro-5-Picoline
• Synonyms: 2-Methoxy-3-Nitro-5-Picoline;Pyridine,2-Methoxy-5-Methyl-3-nitro-;6-Methoxy-5-nitro-3-picoline;2-Methoxy-5-methyl-3-nitropyridine98%
• CAS NO: 33252-62-9
• Molecular Formula: C₇H₈N₂O₃
• Molecular Weight: 168.15002
• Product Categories: Amines;blocks;Pyridines;Pyridine
• Mol File: 33252-62-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 278.8 °C at 760 mmHg
• Flash Point: 122.4 °C
• Appearance: /
• Density: 1.247 g/cm³
• Vapor Pressure: 0.00706mmHg at 25°C
• Refractive Index: 1.541
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Methoxy-3-Nitro-5-Picoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methoxy-3-Nitro-5-Picoline(33252-62-9)
• EPA Substance Registry System: 2-Methoxy-3-Nitro-5-Picoline(33252-62-9)

Safety Data

• Hazardous Substances Data: 33252-62-9(Hazardous Substances Data)

Usage

General Description

2-Methoxy-3-Nitro-5-Picoline is a chemical compound with the molecular formula C7H7NO3. It is a heterocyclic aromatic compound that contains a nitro group, a methoxy group, and a pyridine ring. This chemical is commonly used as an intermediate in the synthesis of agrochemicals, pharmaceuticals, and other organic compounds. It is known for its selective and efficient reactions in various chemical processes, making it a valuable building block for the production of different types of chemicals. Additionally, 2-Methoxy-3-Nitro-5-Picoline exhibits potential biological activities, making it a key target for medicinal chemistry research.

InChI:InChI=1/C7H8N2O3/c1-5-3-6(9(10)11)7(12-2)8-4-5/h3-4H,1-2H3

Upstream product

• 67-56-1 methanol 
• 23056-40-8 2-chloro-5-methyl-3-nitro-pyridine 
• 124-41-4 sodium methylate 
• 7464-14-4 5-methyl-3-nitropyridin-2(1H)-one 

Downstream Products

• 1574636-27-3 (E)-N-(2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)ethanesulfonamide 
• 1574636-32-0 (E)-N-(2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)propane-1-sulfonamide 
• 1574636-08-0 2-methoxy-5-(1-(methylsulfonyl)-2-(piperidin-1-yl)-2-(2,4,6-trimethoxyphenyl)ethyl)-3-nitropyridine 
• 1573056-04-8 1-(2-methoxy-5-methylpyridin-3-yl)-3-[3-methyl-4-(2-methylpyridin-4-yloxy)-benzyl]-urea 
• 1353547-82-6 (E)-2-methoxy-3-nitro-5-((2,4,6-trimethoxystyrylsulfinyl)methyl)pyridine 
• 1353547-80-4 (E)-5-((2,6-dimethoxystyrylsulfonyl)methyl)-2-methoxy-3-nitropyridine 
• 1353547-79-1 (E)-2-((2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)amino)acetamide 
• 1353547-78-0 (E)-N-ethyl-N-(2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)acetamide 
• 1353547-77-9 (E)-2-((2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)amino)acetic acid 
• 1353547-76-8 (E)-ethyl 2-((2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)amino)acetate 
• 1353547-75-7 (E)-N-(2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)methanesulfonamide 
• 1353547-74-6 (E)-N-(2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)acetamide 
• 1353547-73-5 (E)-2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-amine 
• 1353547-72-4 (E)-2-methoxy-3-nitro-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridine 

Relevant articles and documents

TYK2 INHIBITORS AND USES THEREOF

Described herein are compounds that are useful in treating a TYK2-mediated disorder. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, a proliferative disorder, an endocrine disorder, a neurological disorder, or a disorder associated with transplantation.

Discovery of (E)-3-((styrylsulfonyl)methyl)pyridine and (E)-2-((styrylsulfonyl)methyl)pyridine derivatives as anticancer agents: Synthesis, structure-activity relationships, and biological activities

ON01910.Na is a highly effective anticancer agent that induces mitotic arrest and apoptosis. Clinical studies with ON01910 in cancer patients have shown efficacy along with an impressive safety profile. While ON01910 is highly active against cancer cells,

PYRIDIN-2 (1H) -ONE DERIVATIVES USEFUL AS MEDICAMENTS FOR THE TREATMENT OF MYELOPROLIFERATIVE DISORDERS, TRANSPLANT REJECTION, IMMUNE-MEDIATED AND INFLAMMATORY DISEASES

Compoundshaving the chemical structure of formula (I) are disclosed; as well as process for theirpreparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).