332883-48-4

Basic information

• Product Name: (2-Bromo-5-nitrophenyl)methanol
• Synonyms: (2-Bromo-5-nitrophenyl)methanol
• CAS NO: 332883-48-4
• Molecular Formula: C₇H₆BrNO₃
• Molecular Weight: 232.03144
• Mol File: 332883-48-4.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (2-Bromo-5-nitrophenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Bromo-5-nitrophenyl)methanol(332883-48-4)
• EPA Substance Registry System: (2-Bromo-5-nitrophenyl)methanol(332883-48-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 332883-48-4(Hazardous Substances Data)

Usage

General Description

(2-Bromo-5-nitrophenyl)methanol, also known as bromonitrophenylmethanol, is a chemical compound that belongs to the class of organic compounds known as nitrobenzenes. It is a pale yellow solid with the chemical formula C7H6BrNO3. (2-Bromo-5-nitrophenyl)methanol is commonly used as a reagent in organic synthesis, particularly in the preparation of various pharmaceuticals and fine chemicals. It can also be used as an intermediate in the production of dyes and pigments. (2-Bromo-5-nitrophenyl)methanol is known to be toxic if ingested or inhaled and should be handled with caution in laboratory settings.

Upstream product

• 84459-32-5 2-bromo-5-nitrobenzaldehyde 
• 208176-31-2 5-nitro-2-bromobenzoic acid ethyl ester 
• 943-14-6 2-bromo-5-nitrobenzoic acid 
• 6942-36-5 methyl 2-bromo-5-nitrobenzoate 

Downstream Products

• 1806-25-3 2-fluoro-7-nitro-fluorene 
• 6939-05-5 7-chloro-2-nitrofluorene 
• 6638-61-5 2-bromo-7-nitro-9H-fluorene 
• 6957-62-6 7-chloro-fluoren-2-ylamine 
• 363-16-6 7-fluoro-fluoren-2-ylamine 
• 6638-60-4 2-amino-7-bromofluorene 
• 868167-55-9 2-bromo-5-nitrobenzyl methanesulfonate 
• 84459-32-5 2-bromo-5-nitrobenzaldehyde 
• 1134559-00-4 1-bromo-2-(chloromethyl)-4-nitro-benzene 
• 1205555-50-5 [5-nitro-2-(p-tolylethynyl)phenyl]methanol 
• 1308314-44-4 (-)-(2-((2R,4S)-2-(2-(tert-butyldiphenylsilyloxy)ethyl)-4-(triisopropylsilyloxy)-3,4-dihydro-2H-pyran-6-yl)-5-nitrophenyl)methanol 

Relevant articles and documents

(3-(1H-1,2,3-triazole)phenyl)phosphoric acid derivative as well as preparation method and application thereof

The invention relates to the technical field of medicinal chemistry, and discloses a (3-(1H-1,2,3-triazole)phenyl)phosphoric acid derivative derivative as shown in a formula X which is described in the specification. The derivative has good and broad-spec

A Chan-Evans-Lam approach to trisubstituted vinyl ethers

Trisubstituted vinyl ethers were accessedviaChan-Evans-Lam coupling of vinyl trifluoroborates and primary aliphatic alcohols. This approach complements prior methods that required the use of neat liquid alcohol coupling partners. A palladium-catalyzed redox-relay Heck reaction was used to convert several vinyl ethers into aldehyde-functionalized 1,3-dihydroisobenzofurans.

Strategy for Overcoming Full Reversibility of Intermolecular Radical Addition to Aldehydes: Tandem C-H and C-O Bonds Cleaving Cyclization of (Phenoxymethyl)arenes with Carbonyls to Benzofurans

An intermolecular addition of carbon radicals enabled by a cascade radical coupling strategy is developed. It includes an intermolecular alkyl radical addition to a carbonyl group followed by an intramolecular alkoxy radical addition to haloarenes and produces substituted benzofurans in high yields. The radical nature of this reaction is explored by radical trapping experiments and EPR analysis. The mechanism is investigated by KIE experiments and control experiments. This method could provide rapid and practical access to the key intermediate of TAM-16, a safe and potent antibacterial agent for treating tuberculosis, and, therefore, is of great importance for organic synthesis and the pharmaceutical industry.