33315-63-8Relevant articles and documents
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Reiffers,S. et al.
, p. 3001 - 3004 (1971)
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Highly efficient selective monohydrolysis of dialkyl malonates and their derivatives
Niwayama, Satomi,Cho, Hanjoung,Lin, Chunlei
, p. 4434 - 4436 (2008/12/21)
The highly efficient selective monohydrolysis of symmetric diesters has been applied to monohydrolysis of several dialkyl malonates and their derivatives. The best conditions apply 0.8-1.2 equiv of aqueous KOH with a co-solvent, THF or acetonitrile, at 0 °C. The procedure is highly practical, yielding the corresponding half-esters in high yields in a straightforward manner, without inducing decarboxylation. It was found that the selectivity tends to become higher with increased hydrophobicity.
Anticholinergic compounds, composititons and methods of treatment
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, (2008/06/13)
Compounds of the formula STR1 wherein the variables are defined in the specification. The compounds and their salts are soft anticholinergic/antisecretory agents especially useful as mydriatics and as antiperspirants.
