333359-90-3 Usage
Description
(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-methoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, also known as (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-methoxyphenyl)methyl]phenyl]-D-glucitol, is a complex organic compound with a unique molecular structure. It is characterized by its stereochemistry and functional groups, which contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-methoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol is used as an inhibitor of sodium-dependent glucose cotransporter 2 (SGLT2) for the treatment of type 2 diabetes. It works by blocking the reabsorption of glucose in the kidneys, leading to increased glucose excretion and reduced blood glucose levels.
(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-methoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol may also have potential applications in other industries, such as in the development of new drug delivery systems or as a building block for the synthesis of other bioactive compounds. However, further research and development would be required to explore these possibilities.
Check Digit Verification of cas no
The CAS Registry Mumber 333359-90-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,3,3,5 and 9 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 333359-90:
(8*3)+(7*3)+(6*3)+(5*3)+(4*5)+(3*9)+(2*9)+(1*0)=143
143 % 10 = 3
So 333359-90-3 is a valid CAS Registry Number.
333359-90-3Relevant articles and documents
GLUCOPYRANOSE DERIVATIVES USEFUL AS SGLT2 INHIBITORS
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Page/Page column 52; 54, (2020/06/10)
The present invention is directed to glucopyranose derivatives of formula (I), pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by SGLT2 activity. More particularly, the compounds of the present invention are useful in the treatment of for example, Type II diabetes mellitus, Syndrome X, and complications and symptoms associated with said disorders.
THE PRESENT INVENTION RELATES TO PROCESS FOR THE PREPARATION OF D-GLUCITOL, 1,5- ANHYDRO-1-C-[4-CHLORO-3-[[4-[[(3S)-TETRAHYDRO-3-FURANYL] OXY]PHENYL] METHYL]PHENYL]-, (1S) AND ITS CRYSTALLINE FORMS THEREOF.
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Page/Page column 31; 48, (2017/08/22)
The present invention relates to process for the preparation of D-glucitol, 1,5- anhydro-l-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl] methyl]phenyl]-, (1S) formula- 1 and its crystalline forms thereof.
PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS
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Page/Page column 40-42, (2010/04/03)
Provided are processes for the preparation of complexes that are useful in purifying compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The processes can reduce the number of steps needed to obtain the target compounds and the complexes formed in the processes are typically provided in a crystalline form.
