333387-97-6

Basic information

• Product Name: Carbamic acid, (3-oxo-3-phenylpropyl)-, 1,1-dimethylethyl ester
• Synonyms: tert-butyl 3-oxo-3-phenylpropylcarbamate
• CAS NO: 333387-97-6
• Molecular Formula: C14H19NO3
• Molecular Weight: 249.31
• Mol File: 333387-97-6.mol
• Article Data: 16

Chemical Properties

• Melting Point: 61 °C
• CAS DataBase Reference: Carbamic acid, (3-oxo-3-phenylpropyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (3-oxo-3-phenylpropyl)-, 1,1-dimethylethyl ester(333387-97-6)
• EPA Substance Registry System: Carbamic acid, (3-oxo-3-phenylpropyl)-, 1,1-dimethylethyl ester(333387-97-6)

Safety Data

• Hazardous Substances Data: 333387-97-6(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 5053-63-4 3-amino-1-phenylpropan-1-ol 
• 614-16-4 Benzoylacetonitrile 
• 3303-84-2 3-(tert-butyloxycarbonylamino)propionic acid 
• 2038-57-5 3-Phenylpropan-1-amine 
• 257892-43-6 (+/-)-N-(tert-butoxycarbonyl)-3-amino-1-phenylpropan-1-ol 
• 100-58-3 phenylmagnesium bromide 
• 142570-56-7 [2-(methoxy-methyl-carbamoyl)-ethyl]-carbamic acid tert-butyl ester 
• 591-51-5 phenyllithium 
• 98-80-6 phenylboronic acid 
• 73627-97-1 3-hydroxy-3-phenylpropanenitrile 
• 1538-75-6 2,2-dimethylpropanoic anhydride 
• 42116-55-2 methyl 3-tert-butoxycarbonylaminopropionate 

Downstream Products

• 1018783-69-1 tert-butyl 2-(5-(2,5-difluorophenyl)-2-phenyl-2,3-dihydro-1,3,4-thiadiazol-2-yl)ethyl-carbamate 
• 7495-58-1 3-aminium chloro-1-phenylpropan-1-one 
• 1338575-94-2 tert-butyl (3-phenylbut-3-en-1-yl)carbamate 
• 781675-02-3 {2-[3-(2,2-dimethylpropionyl)-5-(2,2-dimethylpropionylamino)-2-phenyl-2,3-dihydro-1,3,4-thiadiazol-2-yl]ethyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

Stereoselective Synthesis of C-Vinyl Glycosides via Palladium-Catalyzed C?H Glycosylation of Alkenes

C-vinyl glycosides are an important class of carbohydrates and pose a unique synthetic challenge. A new strategy has been developed for stereoselective synthesis of C-vinyl glycosides via Pd-catalyzed directed C?H glycosylation of alkenes with glycosyl chloride donors using an easily removable bidentate auxiliary. Both the γ C?H bond of allylamines and the δ C?H bond of homoallyl amine substrates can be glycosylated in high efficiency and with excellent regio- and stereoselectivity. The resulting C-vinyl glycosides can be further converted to a variety of C-alkyl glycosides with high stereospecificity. These reactions offer a broadly applicable method to streamline the synthesis of complex C-vinyl glycosides from easily accessible starting materials.

Palladium-Catalyzed Asymmetric [8+2] Dipolar Cycloadditions of Vinyl Carbamates and Photogenerated Ketenes

Higher-order cycloadditions, particularly [8+2] cycloadditions, are a straightforward and efficient strategy for constructing significant medium-sized architectures. Typically, configuration-restrained conjugated systems are utilized as 8π-components for

Oxyfunctionalization of the Remote C?H Bonds of Aliphatic Amines by Decatungstate Photocatalysis

Aliphatic amines, oxygenated at remote positions within the molecule, represent an important class of synthetic building blocks to which there are currently no direct means of access. Reported herein is an efficient and scalable solution that relies upon decatungstate photocatalysis under acidic conditions using either H2O2 or O2 as the terminal oxidant. By using these reaction conditions a series of simple and unbiased aliphatic amine starting materials can be oxidized to value-added ketone products. Lastly, NMR spectroscopy using in situ LED-irradiated samples was utilized to monitor the kinetics of the reaction, thus enabling direct translation of the reaction into flow.