33354-97-1

Basic information

• Product Name: Piperidine, 2-pentyl-
• Synonyms: 2-Pentylpiperidin;1-Piperidyl-(2)-n-pentan;2-Amyl-piperidin;2-Pentyl-piperidin;2-Pentyl-piperidine;2-pentylpiperidine
• CAS NO: 33354-97-1
• Molecular Formula: C10H21N
• Molecular Weight: 155.283
• Mol File: 33354-97-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 94 - 95 °C (18 mmHg)
• Density: 0.819±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Piperidine, 2-pentyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 2-pentyl-(33354-97-1)
• EPA Substance Registry System: Piperidine, 2-pentyl-(33354-97-1)

Safety Data

• Hazardous Substances Data: 33354-97-1(Hazardous Substances Data)

Upstream product

• 2294-76-0 2-pentylpyridine 
• 2057-43-4 2-(3-pentenyl)pyridine 
• 83688-88-4 N-(5-hexenoyl)-piperidone 
• 5029-67-4 2-iodopyridine 
• 627-19-0 1-Pentyne 
• 202828-84-0 2-(pent-1'-ynyl)-pyridine 
• 34164-50-6 4-penten-1-ylmagnesium bromide 
• 5693-62-9 2,3,4,5-tetrahydro-6-methoxypyridine 
• 112547-27-0 1-bromo-decan-5-one 
• 859815-68-2 1-hydroxydecan-5-one 
• 36394-07-7 5-hexenoyl chloride 
• 532985-81-2 1-pentyl-1-phenylpiperidine 
• 70-55-3 toluene-4-sulfonamide 
• 83688-89-5 6-(4-Pentenyl)-2,3,4,5-tetrahydropyridine 

Relevant articles and documents

A General Catalyst Based on Cobalt Core–Shell Nanoparticles for the Hydrogenation of N-Heteroarenes Including Pyridines

Herein, we report the synthesis of specific silica-supported Co/Co3O4 core–shell based nanoparticles prepared by template synthesis of cobalt-pyromellitic acid on silica and subsequent pyrolysis. The optimal catalyst material allows for general and selective hydrogenation of pyridines, quinolines, and other heteroarenes including acridine, phenanthroline, naphthyridine, quinoxaline, imidazo[1,2-a]pyridine, and indole under comparably mild reaction conditions. In addition, recycling of these Co nanoparticles and their ability for dehydrogenation catalysis are showcased.

Preparation of monoalkylpiperidines via the mild hydrogenation of monoalkynylpyridines

Monoalkynylpyridines were prepared via a Sonogashira cross-coupling reaction between monoiodopyridines and alkynes. Mild hydrogenation of the obtained monoalkynylpyridines was then conducted to produce the corresponding monoalkylpiperidines in moderate to excellent yields. The hydrogenation reaction was carried out under H2 (1?atm) in the presence of 10?wt% Pd/C (5?eq) in either AcOH or MeOH at room temperature. The present mild method is therefore useful for the quick and easy preparation of monoalkylpiperidines.

Dearomatization of N-phenyl-2,6-dialkylpiperidines: Practical synthesis of (±)-solenopsin A and (±)-dihydropinidine

The fire ant venom alkaloid (±)-solenopsin A was prepared in 4 steps (34%) starting from the N-phenyl-2-undecyl piperidine (1c). The key step in this synthesis involved the dearomatization of the phenyl group of N-phenyl-2-methyl-6-undecyl-piperidine (9c), which was carried out under Birch conditions.