333774-32-6

Basic information

• Product Name: 2-(benzoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid
• Synonyms: 2-(benzoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid
• CAS NO: 333774-32-6
• Molecular Weight: 315.393
• Mol File: 333774-32-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(benzoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid(333774-32-6)
• EPA Substance Registry System: 2-(benzoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid(333774-32-6)

Safety Data

• Hazardous Substances Data: 333774-32-6(Hazardous Substances Data)

Usage

General Description

2-(benzoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid is a complex chemical compound with a molecular formula C20H19NO3S. It is a derivative of the cyclic compound cyclohepta[b]thiophene and contains a benzoylamino group and a carboxylic acid group. 2-(benzoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid has potential applications in the pharmaceutical industry, particularly in the development of new medications for various diseases and disorders. Its unique chemical structure may contribute to its ability to interact with biological systems and exert pharmacological effects. Research on this compound is ongoing to explore its potential therapeutic uses and to better understand its properties and mechanisms of action.

Upstream product

• 63274-52-2 2-benzoylamino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid ethyl ester 
• 40106-13-6 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid ethyl ester 
• 885115-88-8 tert-butyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate 
• 1588502-41-3 C₂₁H₂₅NO₃S 
• 502-42-1 cycloheptanone 

Downstream Products

• 107113-11-1 2-phenyl-6,7,8,9-tetrahydro-4H,5H-cyclohepta[4,5]thieno[2,3-d][1,3]oxazin-4-one 
• 328261-61-6 2-benzamido-N-(4-methoxyphenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide 

Relevant articles and documents

FUSED THIOPHENE DERIVATIVES AND THEIR USES

The present invention relates to a new class of fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.

Synthesis and biological evaluation of 2-acetamidothiophene-3-carboxamide derivatives against Leishmania donovani

A high-throughput (HTS) and high-content screening (HCS) campaign of a commercial library identified 2-acetamidothophen-3-carboxamide as a novel scaffold for developing new anti-leishmanial agents. A series of chemical modifications were performed to study the structure-activity relationship (SAR) and in vitro anti-leishmanial activities were evaluated using biological assays of not only extracellular promastigotes but also intracellular amastigotes. Compound 6a showed promising anti-amastigote activity (EC50 = 6.41 μM) against L. donovani without any cytotoxicity (CC50 > 50 μM) towards human macrophages.