33447-90-4

Basic information

• Product Name: hexane-2,5-diyl dimethanesulfonate
• Synonyms: (+-)-2,5-Hexanediol dimesylate; 2,5-Hexanediol, dimethanesulfonate
• CAS NO: 33447-90-4
• Molecular Formula: C₈H₁₈O₆S₂
• Molecular Weight: 274.3549
• Mol File: 33447-90-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 459.8°C at 760 mmHg
• Flash Point: 231.9°C
• Density: 1.269g/cm³
• Vapor Pressure: 3.36E-08mmHg at 25°C
• Refractive Index: 1.468
• CAS DataBase Reference: hexane-2,5-diyl dimethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: hexane-2,5-diyl dimethanesulfonate(33447-90-4)
• EPA Substance Registry System: hexane-2,5-diyl dimethanesulfonate(33447-90-4)

Safety Data

• Hazardous Substances Data: 33447-90-4(Hazardous Substances Data)

Upstream product

• 2935-44-6 hexane-2,5-diol 
• 124-63-0 methanesulfonyl chloride 
• 38484-56-9 (+/-)-2,5-hexanediol 
• 17299-03-5 phthalic acid 1,1'-(meso-1,4-dimethyl-butane-1,4-diyl) ester 
• 42355-32-8 O¹,O⁶-bis-methanesulfonyl-2,3;4,5-dianhydro-allitol 
• 38484-55-8 (2R,5S)-hexanediol 

Relevant articles and documents

Asymmetric synthesis of trans-2,5-dimethylpyrrolidine

A new synthetic route to (2S,5S)-dimethylpyrrolidine 1, which can also be applied to the synthesis of the (2R,5R)-enantiomer, has been developed. The C2-symmetric pyrrolidine can be obtained enantiomerically pure (e.e. ≥ 97%) in 15% overall yield starting from a mixture of isomers of 2,5-hexanediol, via a short reaction sequence using (S)-α-methylbenzylamine as a chiral auxiliary. The crystal and molecular structure of (S)-2'-phenyl-N-ethyl-(2S,5S)-dimethylpyrrolidine picrate 5, showing an antiparallel stacking of the picrate units, is also reported.

Alkylating esters VIII. The action of the isomers of dimethylmyleran on spermatogenesis

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