33458-07-0

Basic information

• Product Name: 1-(4-tert.-Butylphenyl)-1.2-dibromaethan
• Synonyms: 1-(4-tert.-Butylphenyl)-1.2-dibromaethan
• CAS NO: 33458-07-0
• Molecular Weight: 320.067
• Mol File: 33458-07-0.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: 1-(4-tert.-Butylphenyl)-1.2-dibromaethan(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-tert.-Butylphenyl)-1.2-dibromaethan(33458-07-0)
• EPA Substance Registry System: 1-(4-tert.-Butylphenyl)-1.2-dibromaethan(33458-07-0)

Safety Data

• Hazardous Substances Data: 33458-07-0(Hazardous Substances Data)

Upstream product

• 1746-23-2 4-tert-Butylstyrene 
• 943-27-1 4'-t-butylacetophenone 
• 253185-03-4 tert-butylbenzene 

Downstream Products

• 1159013-48-5 2-bromo-1-(4-(tert-butyl)phenyl)ethan-1-ol 
• 92975-15-0 2,3-di(tert-butylphenyl)-1,3-butadiene 
• 1354970-11-8 1-(1-azidovinyl)-4-(tert-butyl)benzene 
• 1621387-08-3 2-((1-(4-(tert-butyl)phenyl)vinyl)oxy)isoindoline-1,3-dione 
• 1621387-23-2 C₁₂H₁₇BO₂ 
• 866358-29-4 1-(1-bromovinyl)-4-(tert-butyl)benzene 

Relevant articles and documents

Dibromination of alkenes with LiBr and H2O2 under mild conditions

Electron-rich and electron-poor alkenes, and alkenes bearing protecting groups can be efficiently and stereoselectively converted to trans-dibromides using LiBr/H2O2 and AcOH as a proton source in 1,4-dioxane. For most substrates addition of 0.1 mol% of PhTeTePh enhances the reaction rate and the yield of the products. Experimental data suggest that the brominating agent prepared in situ is molecular bromine and that LiBr assists the activation of H2O2 allowing bromination to occur using AcOH as a mild proton source in uncatalyzed experiments. Scale-up is feasible: 10.0 mmol of 1-octene was quantitatively converted to 1,2-dibromooctene in one hour of reaction at room temperature.

Electrosynthesis of N-unsubstituted enaminosulfones from vinyl azides and sodium sulfinates mediated by NH4I

A wide range of N-unsubstituted enaminosulfones were obtained via electrochemical sulfonylation of vinyl azides with sulfonyl radicals generated from sodium sulfinates. The discovery of N-unsubstituted enaminosulfones synthesis is based on a unique ability of the azido group to eliminate the N2 molecule. The process is performed under constant current conditions in an experimentally convenient undivided electrochemical cell equipped with a graphite anode and a stainless steel cathode applying NH4I both as the redox catalyst and the supporting electrolyte.

Rh(III)-Catalyzed C-H Activation-Initiated Directed Cyclopropanation of Allylic Alcohols

We have developed a Rh(III)-catalyzed diastereoselective [2+1] annulation onto allylic alcohols initiated by alkenyl C-H activation of N-enoxyphthalimides to furnish substituted cyclopropyl-ketones. Notably, the traceless oxyphthalimide handle serves three functions: directing C-H activation, oxidation of Rh(III), and, collectively with the allylic alcohol, in directing cyclopropanation to control diastereoselectivity. Allylic alcohols are shown to be highly reactive olefin coupling partners leading to a directed diastereoselective cyclopropanation reaction, providing products not accessible by other routes.