33458-29-6

Basic information

• Product Name: Ethanone, 2-[4-(dimethylamino)phenyl]-2-hydroxy-1-phenyl-
• CAS NO: 33458-29-6
• Molecular Formula: C16H17NO2
• Molecular Weight: 255.316
• Mol File: 33458-29-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-[4-(dimethylamino)phenyl]-2-hydroxy-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-[4-(dimethylamino)phenyl]-2-hydroxy-1-phenyl-(33458-29-6)
• EPA Substance Registry System: Ethanone, 2-[4-(dimethylamino)phenyl]-2-hydroxy-1-phenyl-(33458-29-6)

Safety Data

• Hazardous Substances Data: 33458-29-6(Hazardous Substances Data)

Usage

General Description

Ethanone, 2-[4-(dimethylamino)phenyl]-2-hydroxy-1-phenyl- is a chemical compound with the molecular formula C16H17NO2. It is also known as ketotifen, and is commonly used in the treatment of allergic conditions such as allergic rhinitis and asthma. Ketotifen works as a non-competitive H1-antihistamine and mast cell stabilizer, helping to reduce the release of histamine and other inflammatory mediators in the body. It also has anti-inflammatory and bronchodilator properties, making it effective in managing symptoms of allergic diseases. Ketotifen is available in various forms, including tablets, eye drops, and oral syrup, and is generally well-tolerated with few adverse effects.

Upstream product

• 100-10-7 4-dimethylamino-benzaldehyde 
• 100-52-7 benzaldehyde 
• 1075-06-5 2,2-dihydroxy-1-phenyl-ethanone 
• 121-69-7 N,N-dimethyl-aniline 
• 1074-12-0 phenylglyoxal hydrate 
• 613-90-1 benzoyl cyanide 
• 6317-85-7 4-(dimethylamino)benzoin 
• 119-53-9 2-hydroxy-2-phenylacetophenone 

Downstream Products

• 6317-85-7 4-(dimethylamino)benzoin 
• 99052-55-8 4--2,2-dimethyl-5-phenyl-3-imidazolin 
• 79213-82-4 5--2,2-dimethyl-4-phenyl-Δ³-1,3-oxazolin 
• 85004-28-0 (Z)-1-(4-Dimethylamino-phenyl)-2-phenyl-ethene-1,2-dithiol 
• 22711-20-2 1-(4-dimethylaminophenyl)-2-phenyl-1,2-ethanedione 
• 7532-77-6 2,5-Bis-3,6-diphenylpyrazin 
• 6266-95-1 1-phenyl-2-<4-(N,N-dimethylamino)phenyl>ethanone 
• 619-84-1 p-N,N-dimethylaminobenzoic acid 
• 65-85-0 benzoic acid 
• 74266-39-0 2,2-bis-(4-dimethylamino-phenyl)-1-phenyl-ethanone 

Relevant articles and documents

Reaction of Arylglyoxals with Electron-Rich Benzenes and π-Excessive Heterocycles. Facile Synthesis of Heteroaryl α-Acyloins

The reaction of arylglyoxals and their hydrates with electron-rich benzenes and π-excessive heterocycles, if conducted in the absence of catalysts, affords α-benzoins.

Cyclisation of benzils

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SOLVENT EFFECTS ON THE ELECTRONIC STRUCTURE OF BIS(4-DIMETHYLAMINODITHIOBENZYL) NICKEL II(4-DMAB)> FROM UV-VIS AND EPR SPECTRA

The UV-VIS and EPR spectra of solutions of NiII(4-DMAB) in 10 solvents with donor number (DN) from 0.1 to 38.8 have been recorded.The changes in the spectra are explained in terms of a change in symmetry of the NiII(4-DMAB) complex on increase in donor number of the solvent.The symmetry change is from square planar to rhombic bipyramidal with corresponding change in electronic configuration of the nickel ion from d2z2 to d1z2, d1x2-y2.Light was observed to accelerate this structural change.