334873-75-5

Basic information

• Product Name: 2,2-difluoro-3-hydroxy-4-methyl-1-phenylpentan-1-one
• Synonyms: 2,2-difluoro-3-hydroxy-4-methyl-1-phenylpentan-1-one
• CAS NO: 334873-75-5
• Molecular Weight: 228.239
• Mol File: 334873-75-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2-difluoro-3-hydroxy-4-methyl-1-phenylpentan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-difluoro-3-hydroxy-4-methyl-1-phenylpentan-1-one(334873-75-5)
• EPA Substance Registry System: 2,2-difluoro-3-hydroxy-4-methyl-1-phenylpentan-1-one(334873-75-5)

Safety Data

• Hazardous Substances Data: 334873-75-5(Hazardous Substances Data)

Upstream product

• 5908-41-8 benzoyltrimethylsilane 
• 86340-78-5 2,2-difluoro-1-phenyl-1-trimethylsiloxyethene 
• 78-84-2 isobutyraldehyde 

Downstream Products

• 334873-69-7 2,2-difluoro-3-methanesulfonyloxy-4-methyl-1-phenylpentan-1-one 
• 334873-71-1 2,2-difluoro-3-trifluoromethanesulfonyloxy-4-methyl-1-phenylpentan-1-one 

Relevant articles and documents

Mixed organofluorine-organosilicon chemistry. 13. One-pot synthesis of difluoroaldols from acylsilanes and trifluoromethyltrimethylsilane. Application to the synthesis of a difluoro analogue of egomaketone

Difluoroaldol compounds 3 were synthesized in a one-pot procedure involving an acylsilane 1, trifluoromethyltrimethylsilane (TFMTMS), and an aldehyde. The key intermediate of this reaction is a difluoroenoxysilane 2. Ytterbium trifiate proved to be a very