33490-11-8

Basic information

• Product Name: 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-1-15N-1-OXYL
• Synonyms: 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-1-15N-1-OXYL;4-Oxo-TEMPO-1-15N
• CAS NO: 33490-11-8
• Molecular Formula: C9H16NO2 *
• Molecular Weight: 171.24
• EINECS: 220-778-7
• Mol File: 33490-11-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 35 °C(lit.)
• Appearance: /
• CAS DataBase Reference: 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-1-15N-1-OXYL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-1-15N-1-OXYL(33490-11-8)
• EPA Substance Registry System: 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-1-15N-1-OXYL(33490-11-8)

Safety Data

• Hazardous Substances Data: 33490-11-8(Hazardous Substances Data)

Upstream product

• 137003-52-2 <15N>-2,2,6,6-tetramethyl-4-piperidone 

Downstream Products

• 79494-16-9 [15N]-4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl 
• 12169-67-4 cyclohexa-1->5-dienyl 
• 122133-94-2 ⁽¹⁵⁾N-labeled 2,2,6,6-tetramethylpiperid-4-one-1-hydroxyl 

Relevant articles and documents

Time resolved CW-EPR spectroscopy of powdered samples: Electron spin polarization of a nitroxyl radical adsorbed on NaY zeolite, generated by the quenching of excited triplet ketones

Chemically induced dynamic electron polarization (CIDEP) generated in a faujasite zeolite (NAY) by the interaction between a stable free radical (4-oxo-TEMPO) and the triplet state of benzophenone was investigated by time-resolved electron spin resonance spectroscopy (TR-CW-EPR). The TR-CW-EPRs were performed by either pulling a long tube containing powdered zeolite through the EPR cavity during the laser irradiation, or by flowing a liquid transport medium (polydimethylsiloxane) for the zeolite powder, through a flat cell in the EPR cavity. CIDEP was observed for intermolecular triplet quenching (benzophenone triplets with 4-oxo-TEMPO) and intramolecular triplet quenching using a covalently linked TEMPO-benzophenone molecule. The identification of the polarized nitroxide structure was confirmed by employing both 14N and 15N 4-oxo-TEMPO isotopomers. The kinetics of the triplet quenching inside the zeolite were studied by diffuse reflection laser flash photolysis.

The synthesis of EPR differentiable spinlabels and their coupling to uridine

For EPR measurements of RNA, DNA, or proteins, the occurrence of the paramagnetic species is necessary. The aim of this work is to improve the synthesis of two different EPR spinlabels 2,2,6,6-tetra methyl-3,4-dehydro- piperidin-N-oxyl-4-acetylene (TEMPA) 6 and 15N-labeled TEMPA 6* and their coupling to uridine. The yield of the synthesis of TEMPA could be increased to 40% and the second nitroxide 2,2,6,6-tetramethyl-3,4-dehydro-piperidin-15N-oxyl- 4-acetylene 6* could be synthesized with a yield of 11%. Copyright Taylor & Francis Group, LLC.