33533-99-2

Basic information

• Product Name: 6-CHLOROCHROMONE
• Synonyms: 6-CHLOROCHROMONE;6-CHLORO-4H-CHROMEN-4-ONE;6-CHLORO-1-BENZOPYRAN-4(4 H)-ONE;6-CHLOROCHROMONE 97%;6-Chlorochromone (6-Chloro-4H-chromene-4-one);4H-1-Benzopyran-4-one, 6-chloro-
• CAS NO: 33533-99-2
• Molecular Formula: C₉H₅ClO₂
• Molecular Weight: 180.59
• Mol File: 33533-99-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 136-138 °C(lit.)
• Boiling Point: 290.9 °C at 760 mmHg
• Flash Point: 133.8 °C
• Appearance: /
• Density: 1.399 g/cm³
• Vapor Pressure: 0.00202mmHg at 25°C
• Refractive Index: 1.608
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 6-CHLOROCHROMONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLOROCHROMONE(33533-99-2)
• EPA Substance Registry System: 6-CHLOROCHROMONE(33533-99-2)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 33533-99-2(Hazardous Substances Data)

Usage

General Description

6-Chlorochromone is a chemical compound with the molecular formula C9H5ClO2. It is a chlorinated chromone derivative, which is a class of compounds known for their biological and pharmacological properties. 6-Chlorochromone has been studied for its potential antiviral, anti-inflammatory, and antioxidant activities. It has also been investigated for its potential use in the treatment of neurodegenerative diseases. Additionally, 6-Chlorochromone has been used as a precursor in the synthesis of various pharmaceutical compounds and organic materials. Overall, 6-Chlorochromone is a versatile and important chemical with potential applications in various fields.

InChI:InChI=1/C9H5ClO2/c10-6-1-2-9-7(5-6)8(11)3-4-12-9/h1-5H

Upstream product

• 51085-92-8 6-chloro-4-oxo-4H-chromene-3-carboxylic acid 
• 107-97-1 sarcosine 
• 42248-31-7 6-Chloro-4-oxo-4H-chromene-3-carbaldehyde 
• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 73220-32-3 (2E)-1-(5-chloro-2-hydroxyphenyl)-3-(dimethylamino)-2-propen-1-one 
• 62437-99-4 2-hydrazinylpyridine dihydrochloride 

Downstream Products

• 36141-22-7 4-chloro-2-(1-methyl-1H-pyrazol-3-yl)phenol 
• 36141-23-8 4-chloro-2-(1-methyl-1H-pyrazol-5-yl)phenol 
• 1235398-71-6 4-(4-chloro-2-(1-methyl-1H-pyrazol-5-yl)phenoxy)-3-cyano-N-(thiazol-4-yl)benzenesulfonamide 

Relevant articles and documents

Reaction of sarcosine with chromone-3-carbaldehyde and 6,6′- (polymethylenedioxy)di(chromone-3-carbaldehyde)

On treatment with N-methylglycine in DMF, the chromone-3-carbaldehydes 1a-c produce 3-[3-(2-hydroxybenzoyl)-1-methyl-2,5-dihydropyrrol-2-yl]-4H-chromen-4- ones 10a-c and the deformylated products 9a-c, whereas the bischromone derivatives 12a-c give the bis[3-(2-hydroxybenzoyl)-1-methylpyrrole] structures 13a-c.

Benzopyrans : Part 40 - Alumina mediated transformations of 4-oxo-4H-1- benzopyran-3-carbaldehyde, -3-carboxylic acid and their 2-methylhomologues

In contact with alumina, the title aldehyde 1 (R = H, Me, Cl) gives the chromones 5 and 9,12 whereas the acid 2 affords the chromones 7, 10 and acetophenone 23. Alumina converts the aldehyde 3 to the xanthone 14, and the corresponding acid 4 to the chromone 8 and diketone 24.