335332-34-8

Basic information

• Product Name: (1R,2R,3S,5S)-3-(Benzyloxy-phenyl-phosphinoyloxy)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 5-(2-benzyloxycarbonyl-ethylcarbamoyl)-pentyl ester
• CAS NO: 335332-34-8
• Molecular Weight: 690.774
• Mol File: 335332-34-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R,3S,5S)-3-(Benzyloxy-phenyl-phosphinoyloxy)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 5-(2-benzyloxycarbonyl-ethylcarbamoyl)-pentyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,3S,5S)-3-(Benzyloxy-phenyl-phosphinoyloxy)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 5-(2-benzyloxycarbonyl-ethylcarbamoyl)-pentyl ester(335332-34-8)
• EPA Substance Registry System: (1R,2R,3S,5S)-3-(Benzyloxy-phenyl-phosphinoyloxy)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 5-(2-benzyloxycarbonyl-ethylcarbamoyl)-pentyl ester(335332-34-8)

Safety Data

• Hazardous Substances Data: 335332-34-8(Hazardous Substances Data)

Upstream product

• 14529-00-1 benzyl 3-aminopropionate 
• 192697-89-5 (1R,2R,3S,5S)-3-(Benzyloxy-phenyl-phosphinoyloxy)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 5-carboxy-pentyl ester 
• 100-51-6 benzyl alcohol 
• 335332-32-6 (1R,2R,3S,5S)-3-(Benzyloxy-phenyl-phosphinoyloxy)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 5-(2-trimethylsilanyl-ethoxycarbonyl)-pentyl ester 

Relevant articles and documents

Cocaine catalytic antibodies: The primary importance of linker effects

Current treatments for cocaine addiction are not effective. The development of a catalytic monoclonal antibody (mAb) provides a strategy for not only binding, but also degrading cocaine, which offers a broad-based therapy. Hapten design is the central element for programming antibody catalysis. The characteristics of the linker used in classic transition-state analogue phosphonate haptens were shown to be important for obtaining mAbs that hydrolyze the benzoate ester of cocaine.