3354-66-3

Basic information

• Product Name: [2-(1,1-Dimethylethoxy)ethyl]benzene
• Synonyms: [2-(1,1-Dimethylethoxy)ethyl]benzene
• CAS NO: 3354-66-3
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.27
• Mol File: 3354-66-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 224.2°C at 760 mmHg
• Flash Point: 89.5°C
• Appearance: /
• Density: 0.915g/cm³
• Vapor Pressure: 0.138mmHg at 25°C
• Refractive Index: 1.487
• CAS DataBase Reference: [2-(1,1-Dimethylethoxy)ethyl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(1,1-Dimethylethoxy)ethyl]benzene(3354-66-3)
• EPA Substance Registry System: [2-(1,1-Dimethylethoxy)ethyl]benzene(3354-66-3)

Safety Data

• Hazardous Substances Data: 3354-66-3(Hazardous Substances Data)

Usage

Description

[2-(1,1-Dimethylethoxy)ethyl]benzene is a chemical compound characterized by a benzene ring with a 2-(1,1-dimethylethoxy)ethyl group attached to it. This organic compound is known for its sweet, floral scent and is commonly utilized in the fragrance industry.

Uses

Used in Fragrance Industry:
[2-(1,1-Dimethylethoxy)ethyl]benzene is used as a fragrance ingredient for adding a sweet, floral scent to perfumes and other personal care products. Its unique aroma profile makes it a valuable addition to the formulations of various scented products.
Used as a Chemical Intermediate:
In addition to its application in the fragrance industry, [2-(1,1-Dimethylethoxy)ethyl]benzene can also serve as a chemical intermediate in the synthesis of other compounds. Its versatile chemical structure allows it to be a building block for creating a range of different chemical products.
Safety Precautions:
It is crucial to handle [2-(1,1-Dimethylethoxy)ethyl]benzene with care, as it may cause irritation upon contact with the skin or eyes. Additionally, ingestion of this compound can be harmful. Therefore, proper protective equipment and handling procedures should be employed when working with this chemical compound to ensure safety.

InChI:InChI=1/C12H18O/c1-12(2,3)13-10-9-11-7-5-4-6-8-11/h4-8H,9-10H2,1-3H3

Upstream product

• 927-83-3 di-t-butyldiazene 
• 100-42-5 styrene 
• 75-65-0 tert-butyl alcohol 
• 60-12-8 2-phenylethanol 
• 100-44-7 benzyl chloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1634-04-4 tert-butyl methyl ether 
• 100-39-0 benzyl bromide 
• 98946-18-0 tert-Butyl 2,2,2-trichloroacetimidate 

Downstream Products

• 119273-88-0 3-nitrophenethyl tert-butyl ether 

Relevant articles and documents

Compound containing carbon-silicon bond and application thereof

The invention discloses a compound containing a carbon-silicon bond and application of the compound in construction of the carbon-carbon bond. The invention provides an application of a compound containing the carbon-silicon bond as shown in a formula I or a formula I' in a chemical reaction for constructing the carbon-carbon bond, wherein one carbon in the carbon-carbon bond is from carbon connected with silicon in the compound containing the carbon-silicon bond. According to the preparation method, the compound containing the carbon-silicon bond is used for providing a carbon free radical, and the carbon free radical can directly react with carbon provided in another molecule under a mild condition to construct the carbon-carbon bond; the preparation method is wider in substrate application range, is suitable for functional group activated C and carbon free radical substrates, and is also suitable for unactivated C-H bond substrates.

Gold(I)-catalyzed synthesis of unsymmetrical ethers using alcohols as alkylating reagents

A microwave-irradiated alcohol-protecting strategy based on gold catalysis utilizing benzyl alcohol, tert-butyl alcohol and triphenylmethanol as alkylating reagents has been developed. This protecting strategy has wide functional group tolerance with satisfactory yields for the majority of the selected alcohols. The mechanism of this transformation was probed with oxygen-18 isotope labelled alcohols assisted by GC-MS techniques and chemical kinetic experiments. This strategy provides an efficient, straightforward and alternative approach to the preparation of benzyl, tert-butyl and trityl ethers in organic synthesis.

Suzuki coupling of potassium cyclopropyl- and alkoxymethyltrifluoroborates with benzyl chlorides

Efficient Csp3-Csp3 Suzuki couplings have been developed with both potassium cyclopropyl- and alkoxymethyltrifluoroborates. Moderate to good yields have been achieved in the cross-coupling of potassium cyclopropyltrifluoroborate with benzyl chlorides possessing electron-donating or electron-withdrawing substituents. Benzyl chloride was also successfully cross-coupled to potassium alkoxymethyltrifluoroborates derived from primary, secondary, and tertiary alcohols.