335672-35-0

Basic information

• Product Name: ethyl 6-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
• Synonyms: ethyl 6-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
• CAS NO: 335672-35-0
• Molecular Weight: 251.669
• Mol File: 335672-35-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 6-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate(335672-35-0)
• EPA Substance Registry System: ethyl 6-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate(335672-35-0)

Safety Data

• Hazardous Substances Data: 335672-35-0(Hazardous Substances Data)

Upstream product

• 1616798-54-9 (E)-4-chloro-2-styrylaniline 
• 36239-09-5 ethyl chlorocarbonylacetate 

Downstream Products

• 86209-35-0 6-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylic acid 

Relevant articles and documents

Manganese(III) acetate mediated oxidative radical cyclizations of α-substituted N-[(E)-stilben-2-yl]acetamides

A synthetic method of 3-substituted 2-quinolinones from readily available α-substituted N-[(E)-stilben-2-yl]acetamides have been developed. α-Carbonylalkyl radical, produced by the manganese(III) acetate oxidation of N-[(E)-stilben-2-yl]acetamides, undergoes an intramolecular 6-exo-dig cyclization onto the CC bond efficiently and 2-quinolinones was produced. A variety of functional groups, including benzoyl, acetyl, cyano, and ethoxycarbonyl groups, are compatible with the reaction conditions. Under Mn(II)/Co(II)/O2 conditions, these N-[(E)-stilben-2-yl]acetamides were also converted into the corresponding 2-quinolinones effectively and a catalytic amount of manganese(II) acetate was used.