33579-37-2

Basic information

• Product Name: meso-1,2-difluoro-1,2-dichloroethane
• Synonyms: meso-1,2-difluoro-1,2-dichloroethane
• CAS NO: 33579-37-2
• Molecular Weight: 134.941
• Mol File: 33579-37-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: meso-1,2-difluoro-1,2-dichloroethane(CAS DataBase Reference)
• NIST Chemistry Reference: meso-1,2-difluoro-1,2-dichloroethane(33579-37-2)
• EPA Substance Registry System: meso-1,2-difluoro-1,2-dichloroethane(33579-37-2)

Safety Data

• Hazardous Substances Data: 33579-37-2(Hazardous Substances Data)

Upstream product

• 430-88-6 threo-1-bromo-2-fluoro-1,2-dichloroethane 
• 430-88-6 erythro-1-bromo-2-fluoro-1,2-dichloroethane 
• 156-60-5 trans-1,2-dichloroethylene 
• 156-59-2 cis-1,2-Dichloroethylene 

Relevant articles and documents

REACTIONS OF CHLORINE MONOFLUORIDE. REGIOSPECIFICITY AND STEREOCHEMISTRY OF THE SUBSTITUTION OF BROMINE ATOMS BY FLUORINE IN HALOGEN-SUBSTITUTED ALKANES AND ESTERS

Under mild conditions without catalysts chlorine monofluoride substitutes bromine atoms for fluorine in bromine-substituted alkanes and esters.Electron-donating substituents promote the substitution reaction.The following sequence is observed in the reactivity of the bromine atoms at the carbon: tertiary > secondary > primary.Halogen atoms (Cl, F) at a carbon containing a bromine also promotes substitution of the latter by fluorine.The reactivity of the bromine atoms decreases in the following order: CCl2Br(CClFBr) > CHClBr(CHFBr) > CH2Br.An alkoxycarbonyl group at a carbon containing bromine prevents substitution.In a number of cases substitutive fluorination is accompanied by skeletal rearrangements and by migration of chlorine atoms.The stereochemistry of substitutive fluorination was studied for the case of the reaction of erythro- and threo-1-bromo-2-fluoro-1,2-dichloroethanes and 1,2-dibromo-1,3-dichloropropanes with chlorine monofluoride.The probable mechanism of the reaction is discussed.