33644-10-9

Basic information

• Product Name: Ethisolide
• Synonyms: Ethisolide;(-)-3aβ,6aβ-Dihydro-3-methylene-4α-ethylfuro[3,4-b]furan-2,6(3H,4H)-dione;(3aR)-4α-Ethyl-3aβ,6aβ-dihydro-3-methylenefuro[3,4-b]furan-2,6(3H,4H)-dione;(3aβ,6aβ)-3-Methylene-4α-ethylhexahydrofuro[3,4-b]furan-2,6-dione
• CAS NO: 33644-10-9
• Molecular Formula: C9H10O4
• Molecular Weight: 182.1733
• Product Categories: Antibiotic
• Mol File: 33644-10-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 421.1°Cat760mmHg
• Flash Point: 228.9°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 2.67E-07mmHg at 25°C
• Refractive Index: 1.507
• CAS DataBase Reference: Ethisolide(CAS DataBase Reference)
• NIST Chemistry Reference: Ethisolide(33644-10-9)
• EPA Substance Registry System: Ethisolide(33644-10-9)

Safety Data

• Hazardous Substances Data: 33644-10-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H10O4/c1-3-5-6-4(2)8(10)13-7(6)9(11)12-5/h5-7H,2-3H2,1H3/t5-,6+,7+/m0/s1

Upstream product

• 64-18-6 formic acid 
• 67814-68-0 2,3-O-isopropylidene-D-ribofuranose 
• 104206-45-3 (S)-((2R,3R)-2-Ethyl-5-oxo-4-phenylsulfanylmethyl-tetrahydro-furan-3-yl)-hydroxy-acetic acid methyl ester 
• 104206-47-5 (3aS,4R,6aS)-4-Ethyl-3-phenylsulfanylmethyl-dihydro-furo[3,4-b]furan-2,6-dione 
• 76311-87-0 (3aR,4R,6aR)-4-Ethyl-2,6-dioxo-hexahydro-furo[3,4-b]furan-3-carboxylic acid methyl ester 
• 76311-84-7 (3aR,4R,6aR)-2-Amino-4-ethyl-6-oxo-3a,4,6,6a-tetrahydro-furo[3,4-b]furan-3-carboxylic acid methyl ester 
• 76508-26-4 (+/-)-3-bromo-5-ethylfuran-2(5H)-one 
• 76524-14-6 (3aR,4R,6aR)-2-Amino-4-ethyl-6-oxo-3a,4,6,6a-tetrahydro-furo[3,4-b]furan-3-carboxylic acid 4-methoxy-benzyl ester 
• 2407-43-4 5-ethyl-5H-furan-2-one 
• 104206-43-1 (R)-((2S,3R)-2-Ethyl-5-oxo-4-phenylsulfanylmethyl-tetrahydro-furan-3-yl)-(2-trimethylsilanyl-ethoxy)-acetic acid methyl ester 
• 104206-45-3 (R)-((2S,3S,4S)-2-Ethyl-5-oxo-4-phenylsulfanylmethyl-tetrahydro-furan-3-yl)-hydroxy-acetic acid methyl ester 
• 104206-47-5 (3α,3aα,4β,6aα)-(+/-)-4-Ethyldihydro-3-<(phenylthio)methyl>furo<3,4-b>furan-2,6(3H,4H)-dione 
• 104206-47-5 (3S,3aR,4S,6aR)-4-Ethyl-3-phenylsulfanylmethyl-dihydro-furo[3,4-b]furan-2,6-dione 
• 104206-42-0 (R)-((2S,3R)-2-Ethyl-4-methylene-5-oxo-tetrahydro-furan-3-yl)-(2-trimethylsilanyl-ethoxy)-acetic acid 

Relevant articles and documents

Short total syntheses of the avenaciolide family of natural products

The avenaciolide family of natural products are small α-methylene bis-γ-lactones that exhibit a wide variety of biological activities. Herein we report concise syntheses of five members of this family of natural products along with the synthesis of one no

Total Synthesis of Ethisolide from "Naked Sugars"

A total synthesis of (+)-ethisolide was realized from (+/-)-7-oxabicyclohept-5-en-2-one by using a radical cyclization as a key step. - Key Words: Ethisolide, 7-oxabicyclohept-5-en-2-one, radical cyclization.

TOTAL SYNTHESIS OF (-)-ISOAVENACIOLIDE AND (-)-ETHISOLIDE

Natural isoavenaciolide and ethisolide were obtained from two bis-butyrolactone intermediates derived from a common bicyclic ester 8, prepared from D-ribose.