337-53-1

Basic information

• Product Name: Benzenemethanol, a-(difluoromethyl)-a-phenyl-
• CAS NO: 337-53-1
• Molecular Formula: C14H12F2O
• Molecular Weight: 234.245
• Mol File: 337-53-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-(difluoromethyl)-a-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-(difluoromethyl)-a-phenyl-(337-53-1)
• EPA Substance Registry System: Benzenemethanol, a-(difluoromethyl)-a-phenyl-(337-53-1)

Safety Data

• Hazardous Substances Data: 337-53-1(Hazardous Substances Data)

Upstream product

• 454-31-9 ethyl difluoroacetate 
• 395-01-7 2,2-difluoro-1-phenylethanone 
• 98-80-6 phenylboronic acid 
• 119-61-9 benzophenone 
• 58310-28-4 (Difluoromethyl)triphenylphosphonium bromide 
• 65864-64-4 trimethyl(difluoromethyl)silane 
• 530-48-3 1,1-Diphenylethylene 
• 67-56-1 methanol 
• 1093490-31-3 diethyl 1,1-difluoro-2-hydroxy-2,2-diphenylethylphosphonate 
• 861721-58-6 2-benzenesulfonyl-2,2-difluoro-1,1-diphenyl-ethanol 
• 86847-53-2 bis(trimethylsilyl)difluoromethane 
• 73037-95-3 1,1-Difluoro-2-(trifluoromethoxy)-2,2-diphenylethane 
• 390-75-0 2-fluoro-1,1-diphenylethene 

Downstream Products

• 1995-47-7 N-(2,2-Difluor-1,1-diphenyl-aethyl)-benzamid 
• 390-75-0 2-fluoro-1,1-diphenylethene 
• 387-04-2 1,1'-(2,2-difluoro-1,1-ethanediyl)dibenzene 

Relevant articles and documents

Difluromethylphosphonium salt, and preparation method and application thereof

The invention discloses difluromethylphosphonium salt, and a preparation method and application thereof. A synthetic method of the difluromethylphosphonium salt disclosed by the invention comprises the following steps of in a solvent, carrying out a react

Rh-Catalyzed arylation of fluorinated ketones with arylboronic acids

The Rh-catalyzed arylation of fluorinated ketones with boronic acids is reported. This efficient process allows access to fluorinated alcohols in high yields under mild conditions. Competition experiments suggest that difluoromethyl ketones are more reactive than trifluoromethyl ketones in this process, despite their decreased electronic activation, an effect we postulate to be steric in origin.

Nucleophilic difluoromethylation and difluoromethylenation of aldehydes and ketones using diethyl difluoromethylphosphonate

New methodology for difluoromethylation and difluoromethylenation of aldehydes and ketones based on nucleophilic fluorination using diethyl difluoromethylphosphonate (1) was developed.