33721-49-2Relevant articles and documents
Mechanism and processing parameters affecting the formation of methyl methanesulfonate from methanol and methanesulfonic acid: an illustrative example for sulfonate ester impurity formation
Delaney, Ed,Jacq, Karine,Sandra, Pat,David, Frank,Taylor-Worth, Karen,Lipczynski, Andrew,Van, Reif,Elder, David P.,Facchine, Kevin L.,Golec, Simon,Oestrich, Rolf Schulte,Teasdale, Andrew,Eyley, Stephen C.
, p. 429 - 433 (2009)
Sulfonate salts offer useful modification of physicochemical properties of active pharmaceutical ingredients (APIs) containing basic groups, but there are regulatory concerns over the presence of sulfonate esters as potential genotoxic impurities (PGIs).